• Version:
  • 11.0 [archived version]
STRINGSTRING
SREK1IP1 SREK1IP1 FAM133A FAM133A RP9 RP9 SPCS3 SPCS3 C5orf51 C5orf51 C11orf57 C11orf57 ZCCHC2 ZCCHC2 C1orf21 C1orf21 TIMM8B TIMM8B CSNK2A1 CSNK2A1 PIH1D2 PIH1D2
"C11orf57" - Uncharacterized protein NKAPD1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C11orf57Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57 (293 aa)    
Predicted Functional Partners:
PIH1D2
PIH1 domain containing 2; Belongs to the PIH1 family (315 aa)
           
  0.776
RP9
Retinitis pigmentosa 9 protein; Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1 (By similarity) (221 aa)
       
      0.720
SREK1IP1
Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival (155 aa)
       
      0.716
FAM133A
Protein FAM133A; Family with sequence similarity 133 member A (248 aa)
       
      0.694
C5orf51
UPF0600 protein C5orf51; Chromosome 5 open reading frame 51; Belongs to the UPF0600 family (294 aa)
           
  0.670
TIMM8B
Mitochondrial import inner membrane translocase subunit Tim8 B; Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity) (98 aa)
           
  0.634
CSNK2A1
Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] (391 aa)
       
      0.622
C1orf21
Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21 (121 aa)
           
  0.556
ZCCHC2
Zinc finger CCHC-type containing 2 (1178 aa)
           
  0.546
SPCS3
Signal peptidase complex subunit 3; Component of the microsomal signal peptidase complex which removes signal peptides and other N-terminal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (180 aa)
           
  0.545
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]