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  • 11.0 [archived version]
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TECTB TECTB MDGA2 MDGA2 OTOA OTOA TECTA TECTA NTNG2 NTNG2 CNTN5 CNTN5 ALPI ALPI ALPPL2 ALPPL2 GP2 GP2 ALPL ALPL NTNG1 NTNG1
"TECTA" - Alpha-tectorin in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TECTAAlpha-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals; Deafness associated genes (2155 aa)    
Predicted Functional Partners:
OTOA
Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family (1139 aa)
         
  0.979
TECTB
Beta-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals (329 aa)
         
0.935
MDGA2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions; I-set domain containing (956 aa)
     
 
  0.926
NTNG1
Netrin-G1; Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites; Netrins (539 aa)
     
 
  0.907
ALPL
Alkaline phosphatase, tissue-nonspecific isozyme; This isozyme may play a role in skeletal mineralization; Belongs to the alkaline phosphatase family (524 aa)
     
 
  0.906
ALPI
Alkaline phosphatase, intestinal (528 aa)
     
 
    0.906
ALPPL2
Alkaline phosphatase, placental like 2 (532 aa)
     
 
    0.906
GP2
Pancreatic secretory granule membrane major glycoprotein GP2; Glycoprotein 2 (537 aa)
         
0.905
NTNG2
Netrin-G2; Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites; Netrins (530 aa)
     
 
  0.905
CNTN5
Contactin-5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity); Fibronectin type III domain containing (1100 aa)
     
 
  0.904
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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