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  • 11.0 [archived version]
STRINGSTRING
BOD1L2 BOD1L2 CTXN3 CTXN3 BOD1 BOD1 TEKT3 TEKT3 TTC29 TTC29 BOD1L1 BOD1L1 RNF180 RNF180 CEP112 CEP112 ZIC5 ZIC5 FRMPD1 FRMPD1 TEX2 TEX2
"CEP112" - Centrosomal protein 112 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP112Centrosomal protein 112 (955 aa)    
Predicted Functional Partners:
TTC29
Tetratricopeptide repeat domain containing (501 aa)
            
  0.861
BOD1
Biorientation of chromosomes in cell division protein 1; Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles (185 aa)
            
  0.738
TEX2
Testis-expressed protein 2; Testis expressed 2 (1134 aa)
            
  0.690
BOD1L1
Biorientation of chromosomes in cell division protein 1-like 1; Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2- dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM. Does not regulate spindle orientation (3051 aa)
            
  0.626
FRMPD1
FERM and PDZ domain-containing protein 1; Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1; FERM domain containing (1578 aa)
      
   
  0.618
BOD1L2
Biorientation of chromosomes in cell division protein 1-like 2; May play a role in proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles (172 aa)
            
  0.594
TEKT3
Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins (490 aa)
      
   
  0.589
CTXN3
Cortexin-3; Cortexin 3; Belongs to the cortexin family (81 aa)
            
  0.583
RNF180
E3 ubiquitin-protein ligase RNF180; E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2; Ring finger proteins (592 aa)
            
  0.547
ZIC5
Zinc finger protein ZIC 5; Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA (By similarity); Zinc fingers C2H2-type (663 aa)
            
  0.538
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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