KLHL23 protein (human) - STRING database

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KLHL23

Kelch-like protein 23; Kelch like family member 23; BTB domain containing (558 aa)

Predicted Functional Partners:

ZNF551

0.657

CHCHD5

0.637

ACTR10

0.592

LSMEM2

0.577

C18orf32

0.569

TBC1D29

0.567

POLR3D

0.554

ENSG00000259399

0.548

TRIM55

0.526

USP28

0.493

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTR10	KLHL23	ENSP00000254286	ENSP00000376419	Actin related protein 10 homolog; Belongs to the actin family	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	0.592
ACTR10	POLR3D	ENSP00000254286	ENSP00000380904	Actin related protein 10 homolog; Belongs to the actin family	DNA-directed RNA polymerase III subunit RPC4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Ep [...]	0.404
C18orf32	KLHL23	ENSP00000464411	ENSP00000376419	RPL17-C18orf32 readthrough; Chromosome 18 open reading frame 32; Belongs to the universal ribosomal protein uL22 family	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	0.569
CHCHD5	KLHL23	ENSP00000325655	ENSP00000376419	Mitochondrial coiled-coil-helix-coiled-coil-helix domain containing proteins	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	0.637
ENSG00000259399	KLHL23	ENSP00000454021	ENSP00000376419	TGIF2-C20orf24 readthrough	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	0.548
KLHL23	ACTR10	ENSP00000376419	ENSP00000254286	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	Actin related protein 10 homolog; Belongs to the actin family	0.592
KLHL23	C18orf32	ENSP00000376419	ENSP00000464411	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	RPL17-C18orf32 readthrough; Chromosome 18 open reading frame 32; Belongs to the universal ribosomal protein uL22 family	0.569
KLHL23	CHCHD5	ENSP00000376419	ENSP00000325655	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	Mitochondrial coiled-coil-helix-coiled-coil-helix domain containing proteins	0.637
KLHL23	ENSG00000259399	ENSP00000376419	ENSP00000454021	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	TGIF2-C20orf24 readthrough	0.548
KLHL23	LSMEM2	ENSP00000376419	ENSP00000315081	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	Leucine rich single-pass membrane protein 2	0.577
KLHL23	POLR3D	ENSP00000376419	ENSP00000380904	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	DNA-directed RNA polymerase III subunit RPC4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Ep [...]	0.554
KLHL23	TBC1D29	ENSP00000376419	ENSP00000462799	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	TBC1 domain family member 29	0.567
KLHL23	TRIM55	ENSP00000376419	ENSP00000323913	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	Tripartite motif-containing protein 55; May regulate gene expression and protein turnover in muscle cells; Ring finger proteins	0.526
KLHL23	USP28	ENSP00000376419	ENSP00000003302	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	Ubiquitin carboxyl-terminal hydrolase 28; Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN. Also involved in G2 DNA damage checkpoint, by deubiquitinating CLSPN, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C). In contrast, it does not deubiquitinate PLK1. Specifically deubiquitinates MYC in the nucleoplasm, leading to prevent MYC degradation by the proteasome- acts by specifically intera [...]	0.493
KLHL23	ZNF551	ENSP00000376419	ENSP00000282296	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	Zinc finger protein 551; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.657
LSMEM2	KLHL23	ENSP00000315081	ENSP00000376419	Leucine rich single-pass membrane protein 2	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	0.577
LSMEM2	TBC1D29	ENSP00000315081	ENSP00000462799	Leucine rich single-pass membrane protein 2	TBC1 domain family member 29	0.707
LSMEM2	ZNF551	ENSP00000315081	ENSP00000282296	Leucine rich single-pass membrane protein 2	Zinc finger protein 551; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.668
POLR3D	ACTR10	ENSP00000380904	ENSP00000254286	DNA-directed RNA polymerase III subunit RPC4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Ep [...]	Actin related protein 10 homolog; Belongs to the actin family	0.404
POLR3D	KLHL23	ENSP00000380904	ENSP00000376419	DNA-directed RNA polymerase III subunit RPC4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Ep [...]	Kelch-like protein 23; Kelch like family member 23; BTB domain containing	0.554

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