node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMC1 | ARMC2 | ENSP00000276569 | ENSP00000376417 | Armadillo repeat containing 1 | Armadillo repeat containing 2 | 0.709 |
ARMC2 | ARMC1 | ENSP00000376417 | ENSP00000276569 | Armadillo repeat containing 2 | Armadillo repeat containing 1 | 0.709 |
ARMC2 | C10orf11 | ENSP00000376417 | ENSP00000361577 | Armadillo repeat containing 2 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation | 0.564 |
ARMC2 | C6orf203 | ENSP00000376417 | ENSP00000384867 | Armadillo repeat containing 2 | Uncharacterized protein C6orf203; Chromosome 6 open reading frame 203 | 0.518 |
ARMC2 | CCDC38 | ENSP00000376417 | ENSP00000345470 | Armadillo repeat containing 2 | Coiled-coil domain containing 38 | 0.706 |
ARMC2 | CFDP1 | ENSP00000376417 | ENSP00000283882 | Armadillo repeat containing 2 | Craniofacial development protein 1; May play a role during embryogenesis | 0.538 |
ARMC2 | FAM13A | ENSP00000376417 | ENSP00000264344 | Armadillo repeat containing 2 | Protein FAM13A; Family with sequence similarity 13 member A; Belongs to the FAM13 family | 0.520 |
ARMC2 | NEK11 | ENSP00000376417 | ENSP00000372857 | Armadillo repeat containing 2 | Serine/threonine-protein kinase Nek11; Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation | 0.555 |
ARMC2 | RHOBTB3 | ENSP00000376417 | ENSP00000369318 | Armadillo repeat containing 2 | Rho-related BTB domain-containing protein 3; Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9; BTB domain containing | 0.522 |
ARMC2 | SPATA9 | ENSP00000376417 | ENSP00000274432 | Armadillo repeat containing 2 | Spermatogenesis-associated protein 9; May play a role in testicular development/spermatogenesis and may be an important factor in male infertility | 0.690 |
ARMC2 | ZKSCAN3 | ENSP00000376417 | ENSP00000366465 | Armadillo repeat containing 2 | Zinc finger protein with KRAB and SCAN domains 3; Transcriptional factor that binds to the consensus sequence 5’-[GT][AG][AGT]GGGG-3’ and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas; SCAN domain containing | 0.574 |
C10orf11 | ARMC2 | ENSP00000361577 | ENSP00000376417 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation | Armadillo repeat containing 2 | 0.564 |
C10orf11 | CCDC38 | ENSP00000361577 | ENSP00000345470 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation | Coiled-coil domain containing 38 | 0.608 |
C10orf11 | CFDP1 | ENSP00000361577 | ENSP00000283882 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation | Craniofacial development protein 1; May play a role during embryogenesis | 0.449 |
C10orf11 | FAM13A | ENSP00000361577 | ENSP00000264344 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation | Protein FAM13A; Family with sequence similarity 13 member A; Belongs to the FAM13 family | 0.554 |
C10orf11 | RHOBTB3 | ENSP00000361577 | ENSP00000369318 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation | Rho-related BTB domain-containing protein 3; Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9; BTB domain containing | 0.405 |
C10orf11 | SPATA9 | ENSP00000361577 | ENSP00000274432 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation | Spermatogenesis-associated protein 9; May play a role in testicular development/spermatogenesis and may be an important factor in male infertility | 0.651 |
C10orf11 | ZKSCAN3 | ENSP00000361577 | ENSP00000366465 | Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation | Zinc finger protein with KRAB and SCAN domains 3; Transcriptional factor that binds to the consensus sequence 5’-[GT][AG][AGT]GGGG-3’ and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas; SCAN domain containing | 0.485 |
C6orf203 | ARMC2 | ENSP00000384867 | ENSP00000376417 | Uncharacterized protein C6orf203; Chromosome 6 open reading frame 203 | Armadillo repeat containing 2 | 0.518 |
CCDC38 | ARMC2 | ENSP00000345470 | ENSP00000376417 | Coiled-coil domain containing 38 | Armadillo repeat containing 2 | 0.706 |