GPR155 protein (human) - STRING database

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GPR155

Integral membrane protein GPR155; G protein-coupled receptor 155 (870 aa)

Predicted Functional Partners:

SOGA1

0.719

TTC29

0.675

JAKMIP1

0.634

ZFYVE26

0.539

DEPDC4

0.510

PI4K2B

0.507

FAIM2

0.506

GPR137B

0.503

GPR89A

0.491

MAS1

0.490

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DEPDC4	GPR155	ENSP00000396234	ENSP00000376335	DEP domain containing 4	Integral membrane protein GPR155; G protein-coupled receptor 155	0.510
FAIM2	GPR155	ENSP00000321951	ENSP00000376335	Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development; Belongs to the BI1 family. LFG subfamily	Integral membrane protein GPR155; G protein-coupled receptor 155	0.506
GPR137B	GPR155	ENSP00000355551	ENSP00000376335	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	Integral membrane protein GPR155; G protein-coupled receptor 155	0.503
GPR137B	GPR89A	ENSP00000355551	ENSP00000319673	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	G protein-coupled receptor 89A; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance; Belongs to the Golgi pH regulator (TC 1.A.38) family	0.445
GPR155	DEPDC4	ENSP00000376335	ENSP00000396234	Integral membrane protein GPR155; G protein-coupled receptor 155	DEP domain containing 4	0.510
GPR155	FAIM2	ENSP00000376335	ENSP00000321951	Integral membrane protein GPR155; G protein-coupled receptor 155	Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development; Belongs to the BI1 family. LFG subfamily	0.506
GPR155	GPR137B	ENSP00000376335	ENSP00000355551	Integral membrane protein GPR155; G protein-coupled receptor 155	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	0.503
GPR155	GPR89A	ENSP00000376335	ENSP00000319673	Integral membrane protein GPR155; G protein-coupled receptor 155	G protein-coupled receptor 89A; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance; Belongs to the Golgi pH regulator (TC 1.A.38) family	0.491
GPR155	JAKMIP1	ENSP00000376335	ENSP00000386711	Integral membrane protein GPR155; G protein-coupled receptor 155	Janus kinase and microtubule-interacting protein 1; Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements; Belongs to the JAKMIP family	0.634
GPR155	MAS1	ENSP00000376335	ENSP00000252660	Integral membrane protein GPR155; G protein-coupled receptor 155	Proto-oncogene Mas; Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1	0.490
GPR155	PI4K2B	ENSP00000376335	ENSP00000264864	Integral membrane protein GPR155; G protein-coupled receptor 155	Phosphatidylinositol 4-kinase type 2-beta; Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the [...]	0.507
GPR155	SOGA1	ENSP00000376335	ENSP00000237536	Integral membrane protein GPR155; G protein-coupled receptor 155	Protein SOGA1; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner; Belongs to the SOGA family	0.719
GPR155	TTC29	ENSP00000376335	ENSP00000423505	Integral membrane protein GPR155; G protein-coupled receptor 155	Tetratricopeptide repeat domain containing	0.675
GPR155	ZFYVE26	ENSP00000376335	ENSP00000251119	Integral membrane protein GPR155; G protein-coupled receptor 155	Zinc finger FYVE domain-containing protein 26; Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis- recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair; Zinc fingers FYVE-type	0.539
GPR89A	GPR137B	ENSP00000319673	ENSP00000355551	G protein-coupled receptor 89A; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance; Belongs to the Golgi pH regulator (TC 1.A.38) family	Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family	0.445
GPR89A	GPR155	ENSP00000319673	ENSP00000376335	G protein-coupled receptor 89A; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance; Belongs to the Golgi pH regulator (TC 1.A.38) family	Integral membrane protein GPR155; G protein-coupled receptor 155	0.491
JAKMIP1	GPR155	ENSP00000386711	ENSP00000376335	Janus kinase and microtubule-interacting protein 1; Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements; Belongs to the JAKMIP family	Integral membrane protein GPR155; G protein-coupled receptor 155	0.634
MAS1	GPR155	ENSP00000252660	ENSP00000376335	Proto-oncogene Mas; Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1	Integral membrane protein GPR155; G protein-coupled receptor 155	0.490
MAS1	SOGA1	ENSP00000252660	ENSP00000237536	Proto-oncogene Mas; Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1	Protein SOGA1; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner; Belongs to the SOGA family	0.595
MAS1	TTC29	ENSP00000252660	ENSP00000423505	Proto-oncogene Mas; Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1	Tetratricopeptide repeat domain containing	0.574

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