KIAA1683 protein (human) - STRING database

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KIAA1683

IQ domain-containing protein N; KIAA1683 (1367 aa)

Predicted Functional Partners:

ZNF559

0.670

CCDC154

0.670

C2orf81

0.670

TCEB3B

0.598

ZNF444

0.596

C7orf73

0.590

SPOPL

0.585

SSBP4

0.563

PGPEP1

0.558

ZC3H8

0.556

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C2orf81	C7orf73	ENSP00000290390	ENSP00000425996	Uncharacterized protein C2orf81; Chromosome 2 open reading frame 81	Short transmembrane mitochondrial protein 1; Chromosome 7 open reading frame 73	0.709
C2orf81	CCDC154	ENSP00000290390	ENSP00000373828	Uncharacterized protein C2orf81; Chromosome 2 open reading frame 81	Coiled-coil domain containing 154	0.789
C2orf81	KIAA1683	ENSP00000290390	ENSP00000376213	Uncharacterized protein C2orf81; Chromosome 2 open reading frame 81	IQ domain-containing protein N; KIAA1683	0.670
C2orf81	TCEB3B	ENSP00000290390	ENSP00000331302	Uncharacterized protein C2orf81; Chromosome 2 open reading frame 81	Elongin-A2; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex)	0.708
C7orf73	C2orf81	ENSP00000425996	ENSP00000290390	Short transmembrane mitochondrial protein 1; Chromosome 7 open reading frame 73	Uncharacterized protein C2orf81; Chromosome 2 open reading frame 81	0.709
C7orf73	CCDC154	ENSP00000425996	ENSP00000373828	Short transmembrane mitochondrial protein 1; Chromosome 7 open reading frame 73	Coiled-coil domain containing 154	0.709
C7orf73	KIAA1683	ENSP00000425996	ENSP00000376213	Short transmembrane mitochondrial protein 1; Chromosome 7 open reading frame 73	IQ domain-containing protein N; KIAA1683	0.590
C7orf73	TCEB3B	ENSP00000425996	ENSP00000331302	Short transmembrane mitochondrial protein 1; Chromosome 7 open reading frame 73	Elongin-A2; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex)	0.669
CCDC154	C2orf81	ENSP00000373828	ENSP00000290390	Coiled-coil domain containing 154	Uncharacterized protein C2orf81; Chromosome 2 open reading frame 81	0.789
CCDC154	C7orf73	ENSP00000373828	ENSP00000425996	Coiled-coil domain containing 154	Short transmembrane mitochondrial protein 1; Chromosome 7 open reading frame 73	0.709
CCDC154	KIAA1683	ENSP00000373828	ENSP00000376213	Coiled-coil domain containing 154	IQ domain-containing protein N; KIAA1683	0.670
CCDC154	TCEB3B	ENSP00000373828	ENSP00000331302	Coiled-coil domain containing 154	Elongin-A2; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex)	0.708
KIAA1683	C2orf81	ENSP00000376213	ENSP00000290390	IQ domain-containing protein N; KIAA1683	Uncharacterized protein C2orf81; Chromosome 2 open reading frame 81	0.670
KIAA1683	C7orf73	ENSP00000376213	ENSP00000425996	IQ domain-containing protein N; KIAA1683	Short transmembrane mitochondrial protein 1; Chromosome 7 open reading frame 73	0.590
KIAA1683	CCDC154	ENSP00000376213	ENSP00000373828	IQ domain-containing protein N; KIAA1683	Coiled-coil domain containing 154	0.670
KIAA1683	PGPEP1	ENSP00000376213	ENSP00000269919	IQ domain-containing protein N; KIAA1683	Pyroglutamyl-peptidase 1; Removes 5-oxoproline from various penultimate amino acid residues except L-proline	0.558
KIAA1683	SPOPL	ENSP00000376213	ENSP00000280098	IQ domain-containing protein N; KIAA1683	Speckle-type POZ protein-like; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes [...]	0.585
KIAA1683	SSBP4	ENSP00000376213	ENSP00000270061	IQ domain-containing protein N; KIAA1683	Single stranded DNA binding protein 4	0.563
KIAA1683	TCEB3B	ENSP00000376213	ENSP00000331302	IQ domain-containing protein N; KIAA1683	Elongin-A2; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex)	0.598
KIAA1683	ZC3H8	ENSP00000376213	ENSP00000386488	IQ domain-containing protein N; KIAA1683	Zinc finger CCCH domain-containing protein 8; Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5’-AGGTCTC-3’ sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis; Zinc fingers CCCH-type	0.556

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