MFSD6 protein (human) - STRING database

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Score

MFSD6

Major facilitator superfamily domain containing 6 (791 aa)

Predicted Functional Partners:

ZNF384

0.815

TMEM194B

0.724

MFSD12

0.700

FAM73A

0.694

MFSD9

0.682

CSGALNACT2

0.678

TMTC2

0.658

C19orf12

0.657

TMEM180

0.649

HMOX2

0.641

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C19orf12	CSGALNACT2	ENSP00000376103	ENSP00000363590	Protein C19orf12; Chromosome 19 open reading frame 12	Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains	0.631
C19orf12	FAM73A	ENSP00000376103	ENSP00000393675	Protein C19orf12; Chromosome 19 open reading frame 12	Mitoguardin 1; Regulator of mitochondrial fusion- acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family	0.658
C19orf12	MFSD6	ENSP00000376103	ENSP00000376141	Protein C19orf12; Chromosome 19 open reading frame 12	Major facilitator superfamily domain containing 6	0.657
CSGALNACT2	C19orf12	ENSP00000363590	ENSP00000376103	Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains	Protein C19orf12; Chromosome 19 open reading frame 12	0.631
CSGALNACT2	FAM73A	ENSP00000363590	ENSP00000393675	Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains	Mitoguardin 1; Regulator of mitochondrial fusion- acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family	0.602
CSGALNACT2	MFSD6	ENSP00000363590	ENSP00000376141	Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains	Major facilitator superfamily domain containing 6	0.678
FAM73A	C19orf12	ENSP00000393675	ENSP00000376103	Mitoguardin 1; Regulator of mitochondrial fusion- acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family	Protein C19orf12; Chromosome 19 open reading frame 12	0.658
FAM73A	CSGALNACT2	ENSP00000393675	ENSP00000363590	Mitoguardin 1; Regulator of mitochondrial fusion- acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family	Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains	0.602
FAM73A	MFSD6	ENSP00000393675	ENSP00000376141	Mitoguardin 1; Regulator of mitochondrial fusion- acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family	Major facilitator superfamily domain containing 6	0.694
HMOX2	MFSD6	ENSP00000477572	ENSP00000376141	Heme oxygenase 2; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter	Major facilitator superfamily domain containing 6	0.641
MFSD12	MFSD6	ENSP00000347583	ENSP00000376141	Major facilitator superfamily domain containing 12	Major facilitator superfamily domain containing 6	0.700
MFSD12	MFSD9	ENSP00000347583	ENSP00000258436	Major facilitator superfamily domain containing 12	Major facilitator superfamily domain containing 9	0.773
MFSD12	TMEM180	ENSP00000347583	ENSP00000238936	Major facilitator superfamily domain containing 12	Transmembrane protein 180	0.771
MFSD6	C19orf12	ENSP00000376141	ENSP00000376103	Major facilitator superfamily domain containing 6	Protein C19orf12; Chromosome 19 open reading frame 12	0.657
MFSD6	CSGALNACT2	ENSP00000376141	ENSP00000363590	Major facilitator superfamily domain containing 6	Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains	0.678
MFSD6	FAM73A	ENSP00000376141	ENSP00000393675	Major facilitator superfamily domain containing 6	Mitoguardin 1; Regulator of mitochondrial fusion- acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family	0.694
MFSD6	HMOX2	ENSP00000376141	ENSP00000477572	Major facilitator superfamily domain containing 6	Heme oxygenase 2; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter	0.641
MFSD6	MFSD12	ENSP00000376141	ENSP00000347583	Major facilitator superfamily domain containing 6	Major facilitator superfamily domain containing 12	0.700
MFSD6	MFSD9	ENSP00000376141	ENSP00000258436	Major facilitator superfamily domain containing 6	Major facilitator superfamily domain containing 9	0.682
MFSD6	TMEM180	ENSP00000376141	ENSP00000238936	Major facilitator superfamily domain containing 6	Transmembrane protein 180	0.649

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