| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARMCX4 | ZNF605 | ENSP00000404304 | ENSP00000376135 | Armadillo repeat containing, X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family | Zinc finger protein 605; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.532 |
| FAIM3 | TMEM178B | ENSP00000356058 | ENSP00000456594 | Fas apoptotic inhibitory molecule 3; May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation | Transmembrane protein 178B | 0.431 |
| FAIM3 | ZNF605 | ENSP00000356058 | ENSP00000376135 | Fas apoptotic inhibitory molecule 3; May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation | Zinc finger protein 605; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.520 |
| FOXJ3 | TMEM178B | ENSP00000361653 | ENSP00000456594 | Forkhead box protein J3; Transcriptional activator of MEF2C involved in the regulation pf adult muscle fiber type identity and skeletal muscle regeneration; Forkhead boxes | Transmembrane protein 178B | 0.411 |
| FOXJ3 | ZNF605 | ENSP00000361653 | ENSP00000376135 | Forkhead box protein J3; Transcriptional activator of MEF2C involved in the regulation pf adult muscle fiber type identity and skeletal muscle regeneration; Forkhead boxes | Zinc finger protein 605; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.531 |
| GALR1 | ZNF605 | ENSP00000299727 | ENSP00000376135 | Galanin receptor type 1; Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity; Belongs to the G-protein coupled receptor 1 family | Zinc finger protein 605; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.501 |
| NABP1 | TMEM178B | ENSP00000403683 | ENSP00000456594 | SOSS complex subunit B2; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-s [...] | Transmembrane protein 178B | 0.418 |
| NABP1 | ZNF605 | ENSP00000403683 | ENSP00000376135 | SOSS complex subunit B2; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-s [...] | Zinc finger protein 605; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.511 |
| NOC4L | ZNF605 | ENSP00000328854 | ENSP00000376135 | Nucleolar complex protein 4 homolog; Armadillo-like helical domain containing; Belongs to the CBF/MAK21 family | Zinc finger protein 605; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.504 |
| TMEM178B | FAIM3 | ENSP00000456594 | ENSP00000356058 | Transmembrane protein 178B | Fas apoptotic inhibitory molecule 3; May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation | 0.431 |
| TMEM178B | FOXJ3 | ENSP00000456594 | ENSP00000361653 | Transmembrane protein 178B | Forkhead box protein J3; Transcriptional activator of MEF2C involved in the regulation pf adult muscle fiber type identity and skeletal muscle regeneration; Forkhead boxes | 0.411 |
| TMEM178B | NABP1 | ENSP00000456594 | ENSP00000403683 | Transmembrane protein 178B | SOSS complex subunit B2; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-s [...] | 0.418 |
| TMEM178B | YIPF4 | ENSP00000456594 | ENSP00000238831 | Transmembrane protein 178B | Protein YIPF4; Involved in the maintenance of the Golgi structure; Belongs to the YIP1 family | 0.518 |
| TMEM178B | YTHDC1 | ENSP00000456594 | ENSP00000339245 | Transmembrane protein 178B | YTH domain-containing protein 1; Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non- coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a key regulator of exon-inclusion or exon-skipping during alternative splicing via interaction with mRNA splicing factors SRSF3 and SRSF10. Specifically binds m6A- containing mRNAs and promotes recruitment of SRSF3 to its mRNA- binding elements adjacent to m6A sites, leadin [...] | 0.493 |
| TMEM178B | ZNF605 | ENSP00000456594 | ENSP00000376135 | Transmembrane protein 178B | Zinc finger protein 605; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.617 |
| TRIM28 | ZNF605 | ENSP00000253024 | ENSP00000376135 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 605; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.903 |
| YIPF4 | TMEM178B | ENSP00000238831 | ENSP00000456594 | Protein YIPF4; Involved in the maintenance of the Golgi structure; Belongs to the YIP1 family | Transmembrane protein 178B | 0.518 |
| YIPF4 | YTHDC1 | ENSP00000238831 | ENSP00000339245 | Protein YIPF4; Involved in the maintenance of the Golgi structure; Belongs to the YIP1 family | YTH domain-containing protein 1; Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non- coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a key regulator of exon-inclusion or exon-skipping during alternative splicing via interaction with mRNA splicing factors SRSF3 and SRSF10. Specifically binds m6A- containing mRNAs and promotes recruitment of SRSF3 to its mRNA- binding elements adjacent to m6A sites, leadin [...] | 0.433 |
| YIPF4 | ZNF605 | ENSP00000238831 | ENSP00000376135 | Protein YIPF4; Involved in the maintenance of the Golgi structure; Belongs to the YIP1 family | Zinc finger protein 605; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.576 |
| YTHDC1 | TMEM178B | ENSP00000339245 | ENSP00000456594 | YTH domain-containing protein 1; Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non- coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a key regulator of exon-inclusion or exon-skipping during alternative splicing via interaction with mRNA splicing factors SRSF3 and SRSF10. Specifically binds m6A- containing mRNAs and promotes recruitment of SRSF3 to its mRNA- binding elements adjacent to m6A sites, leadin [...] | Transmembrane protein 178B | 0.493 |
