• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM73A FAM73A VSTM2B VSTM2B PANK2 PANK2 C19orf12 C19orf12 DCAF17 DCAF17 PLA2G6 PLA2G6 WDR45 WDR45 ENSG00000250232 ENSG00000250232 FA2H FA2H ATP13A2 ATP13A2 PANK1 PANK1
"C19orf12" - Protein C19orf12 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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C19orf12Protein C19orf12; Chromosome 19 open reading frame 12 (152 aa)    
Predicted Functional Partners:
PANK2
Pantothenate kinase 2, mitochondrial; May be the master regulator of the CoA biosynthesis; Belongs to the type II pantothenate kinase family (570 aa)
           
  0.802
FA2H
Fatty acid 2-hydroxylase; Required for alpha-hydroxylation of free fatty acids and the formation of alpha-hydroxylated sphingolipids; Belongs to the sterol desaturase family. SCS7 subfamily (372 aa)
           
  0.766
ENSG00000250232
PRA1 family protein; Uncharacterized protein; WD repeat domain phosphoinositide-interacting protein 4 (292 aa)
           
  0.765
WDR45
WD repeat domain phosphoinositide-interacting protein 4; Plays an important role in the autophagy pathway, which is the major intracellular degradation system by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation; Belongs to the WD repeat SVP1 family (361 aa)
           
  0.760
PANK1
Pantothenate kinase 1; Plays a role in the physiological regulation of the intracellular CoA concentration; Belongs to the type II pantothenate kinase family (598 aa)
           
  0.739
DCAF17
DDB1- and CUL4-associated factor 17; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors (520 aa)
           
  0.735
PLA2G6
85/88 kDa calcium-independent phospholipase A2; Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F- actin polymerization at the pseudopods; Anky [...] (806 aa)
           
  0.730
VSTM2B
V-set and transmembrane domain containing 2B (285 aa)
           
  0.697
ATP13A2
Cation-transporting ATPase 13A2; ATPase that plays a role in intracellular cation homeostasis and the maintenance of neuronal integrity. Required for a proper lysosomal and mitochondrial maintenance; ATPase orphan transporters (1180 aa)
           
  0.670
FAM73A
Mitoguardin 1; Regulator of mitochondrial fusion- acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family (633 aa)
           
  0.658
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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