ZSCAN5A protein (human) - STRING database

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ZSCAN5A

Zinc finger and SCAN domain-containing protein 5A; May be involved in transcriptional regulation; SCAN domain containing (496 aa)

Predicted Functional Partners:

CXorf40B

0.659

ALOXE3

0.585

POLR3A

0.540

RUFY2

0.473

TRIM43

0.466

KLHL11

0.450

HES7

0.444

KHDC1

0.441

PBLD

0.440

CCSAP

0.429

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALOXE3	HES7	ENSP00000314879	ENSP00000446205	Hydroperoxide isomerase ALOXE3; Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compared to other lipoxygenases. The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols. The dioxygenase activity requires a step of activation of the enzyme by molecular oxygen. In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty [...]	Transcription factor HES-7; Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity); Basic helix-loop-helix proteins	0.763
ALOXE3	ZSCAN5A	ENSP00000314879	ENSP00000375593	Hydroperoxide isomerase ALOXE3; Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compared to other lipoxygenases. The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols. The dioxygenase activity requires a step of activation of the enzyme by molecular oxygen. In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty [...]	Zinc finger and SCAN domain-containing protein 5A; May be involved in transcriptional regulation; SCAN domain containing	0.585
CCSAP	CXorf40B	ENSP00000284617	ENSP00000359434	Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating (By similarity)	Protein CXorf40B; Chromosome X open reading frame 40B	0.551
CCSAP	KLHL11	ENSP00000284617	ENSP00000314608	Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating (By similarity)	Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation; BTB domain containing	0.496
CCSAP	ZSCAN5A	ENSP00000284617	ENSP00000375593	Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating (By similarity)	Zinc finger and SCAN domain-containing protein 5A; May be involved in transcriptional regulation; SCAN domain containing	0.429
CXorf40B	CCSAP	ENSP00000359434	ENSP00000284617	Protein CXorf40B; Chromosome X open reading frame 40B	Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating (By similarity)	0.551
CXorf40B	KHDC1	ENSP00000359434	ENSP00000359411	Protein CXorf40B; Chromosome X open reading frame 40B	KH homology domain-containing protein 1; KH domain containing 1; Belongs to the KHDC1 family	0.557
CXorf40B	KLHL11	ENSP00000359434	ENSP00000314608	Protein CXorf40B; Chromosome X open reading frame 40B	Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation; BTB domain containing	0.557
CXorf40B	TRIM43	ENSP00000359434	ENSP00000272395	Protein CXorf40B; Chromosome X open reading frame 40B	Tripartite motif containing 43; Ring finger proteins	0.559
CXorf40B	ZSCAN5A	ENSP00000359434	ENSP00000375593	Protein CXorf40B; Chromosome X open reading frame 40B	Zinc finger and SCAN domain-containing protein 5A; May be involved in transcriptional regulation; SCAN domain containing	0.659
HES7	ALOXE3	ENSP00000446205	ENSP00000314879	Transcription factor HES-7; Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity); Basic helix-loop-helix proteins	Hydroperoxide isomerase ALOXE3; Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced dioxygenase activity compared to other lipoxygenases. The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols. The dioxygenase activity requires a step of activation of the enzyme by molecular oxygen. In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty [...]	0.763
HES7	ZSCAN5A	ENSP00000446205	ENSP00000375593	Transcription factor HES-7; Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity); Basic helix-loop-helix proteins	Zinc finger and SCAN domain-containing protein 5A; May be involved in transcriptional regulation; SCAN domain containing	0.444
KHDC1	CXorf40B	ENSP00000359411	ENSP00000359434	KH homology domain-containing protein 1; KH domain containing 1; Belongs to the KHDC1 family	Protein CXorf40B; Chromosome X open reading frame 40B	0.557
KHDC1	TRIM43	ENSP00000359411	ENSP00000272395	KH homology domain-containing protein 1; KH domain containing 1; Belongs to the KHDC1 family	Tripartite motif containing 43; Ring finger proteins	0.491
KHDC1	ZSCAN5A	ENSP00000359411	ENSP00000375593	KH homology domain-containing protein 1; KH domain containing 1; Belongs to the KHDC1 family	Zinc finger and SCAN domain-containing protein 5A; May be involved in transcriptional regulation; SCAN domain containing	0.441
KLHL11	CCSAP	ENSP00000314608	ENSP00000284617	Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation; BTB domain containing	Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating (By similarity)	0.496
KLHL11	CXorf40B	ENSP00000314608	ENSP00000359434	Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation; BTB domain containing	Protein CXorf40B; Chromosome X open reading frame 40B	0.557
KLHL11	ZSCAN5A	ENSP00000314608	ENSP00000375593	Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation; BTB domain containing	Zinc finger and SCAN domain-containing protein 5A; May be involved in transcriptional regulation; SCAN domain containing	0.450
PBLD	RUFY2	ENSP00000351619	ENSP00000373420	Phenazine biosynthesis like protein domain containing	RUN and FYVE domain containing 2; Zinc fingers FYVE-type	0.709
PBLD	ZSCAN5A	ENSP00000351619	ENSP00000375593	Phenazine biosynthesis like protein domain containing	Zinc finger and SCAN domain-containing protein 5A; May be involved in transcriptional regulation; SCAN domain containing	0.440

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