FAM127C protein (human) - STRING database

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FAM127C

Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family (113 aa)

Predicted Functional Partners:

ZCCHC5

0.709

PEG10

0.590

RGAG1

0.564

ZCCHC16

0.560

TCEAL5

0.550

PNMA6A

0.542

BEX5

0.510

FTHL17

0.507

ZXDA

0.475

TCEAL3

0.464

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BEX5	FAM127C	ENSP00000446054	ENSP00000375268	Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	0.510
BEX5	FTHL17	ENSP00000446054	ENSP00000368207	Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family	Ferritin heavy chain like 17	0.445
BEX5	TCEAL3	ENSP00000446054	ENSP00000361711	Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family	Transcription elongation factor A protein-like 3; May be involved in transcriptional regulation; Transcription elongation factor A like family	0.701
BEX5	TCEAL5	ENSP00000446054	ENSP00000361765	Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family	Transcription elongation factor A protein-like 5; May be involved in transcriptional regulation; Transcription elongation factor A like family	0.749
FAM127C	BEX5	ENSP00000375268	ENSP00000446054	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family	0.510
FAM127C	FTHL17	ENSP00000375268	ENSP00000368207	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	Ferritin heavy chain like 17	0.507
FAM127C	PEG10	ENSP00000375268	ENSP00000418944	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	Retrotransposon-derived protein PEG10; Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5’-GCCTGTCTTT-3’ DNA sequence of the MB1 domain in the myelin basic protein (M [...]	0.590
FAM127C	PNMA6A	ENSP00000375268	ENSP00000391488	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	Paraneoplastic antigen-like protein 6A; Paraneoplastic Ma antigens; Belongs to the PNMA family	0.542
FAM127C	RGAG1	ENSP00000375268	ENSP00000419786	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	Retrotransposon Gag-like protein 9; Retrotransposon gag domain containing 1	0.564
FAM127C	TCEAL3	ENSP00000375268	ENSP00000361711	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	Transcription elongation factor A protein-like 3; May be involved in transcriptional regulation; Transcription elongation factor A like family	0.464
FAM127C	TCEAL5	ENSP00000375268	ENSP00000361765	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	Transcription elongation factor A protein-like 5; May be involved in transcriptional regulation; Transcription elongation factor A like family	0.550
FAM127C	ZCCHC16	ENSP00000375268	ENSP00000340590	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	Retrotransposon Gag-like protein 4; Involved in cognitive function in the brain, possibly via the noradrenergic system	0.560
FAM127C	ZCCHC5	ENSP00000375268	ENSP00000316794	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	Retrotransposon Gag-like protein 3; May function as a transcriptional regulator. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal	0.709
FAM127C	ZXDA	ENSP00000375268	ENSP00000351530	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	Zinc finger X-linked protein ZXDA; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes; Zinc fingers C2H2-type	0.475
FTHL17	BEX5	ENSP00000368207	ENSP00000446054	Ferritin heavy chain like 17	Protein BEX5; Brain expressed X-linked family; Belongs to the BEX family	0.445
FTHL17	FAM127C	ENSP00000368207	ENSP00000375268	Ferritin heavy chain like 17	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	0.507
FTHL17	TCEAL5	ENSP00000368207	ENSP00000361765	Ferritin heavy chain like 17	Transcription elongation factor A protein-like 5; May be involved in transcriptional regulation; Transcription elongation factor A like family	0.512
PEG10	FAM127C	ENSP00000418944	ENSP00000375268	Retrotransposon-derived protein PEG10; Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5’-GCCTGTCTTT-3’ DNA sequence of the MB1 domain in the myelin basic protein (M [...]	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	0.590
PNMA6A	FAM127C	ENSP00000391488	ENSP00000375268	Paraneoplastic antigen-like protein 6A; Paraneoplastic Ma antigens; Belongs to the PNMA family	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	0.542
RGAG1	FAM127C	ENSP00000419786	ENSP00000375268	Retrotransposon Gag-like protein 9; Retrotransposon gag domain containing 1	Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member C; Belongs to the FAM127 family	0.564

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