| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ETF1 | FAM127B | ENSP00000353741 | ENSP00000375267 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | 0.513 |
| FAM127B | ETF1 | ENSP00000375267 | ENSP00000353741 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons | 0.513 |
| FAM127B | MOSPD1 | ENSP00000375267 | ENSP00000359819 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to- mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation | 0.540 |
| FAM127B | PEG10 | ENSP00000375267 | ENSP00000418944 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | Retrotransposon-derived protein PEG10; Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5’-GCCTGTCTTT-3’ DNA sequence of the MB1 domain in the myelin basic protein (M [...] | 0.557 |
| FAM127B | PRRG1 | ENSP00000375267 | ENSP00000444278 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | Transmembrane gamma-carboxyglutamic acid protein 1; Proline rich and Gla domain containing | 0.516 |
| FAM127B | RGAG1 | ENSP00000375267 | ENSP00000419786 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | Retrotransposon Gag-like protein 9; Retrotransposon gag domain containing 1 | 0.484 |
| FAM127B | RGAG4 | ENSP00000375267 | ENSP00000476792 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | Retrotransposon Gag-like protein 5; Retrotransposon gag domain containing 4 | 0.641 |
| FAM127B | SLC10A3 | ENSP00000375267 | ENSP00000263512 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | P3 protein; The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions; Solute carriers | 0.446 |
| FAM127B | ZBTB21 | ENSP00000375267 | ENSP00000308759 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | Zinc finger and BTB domain-containing protein 21; Acts as a transcription repressor; BTB domain containing | 0.420 |
| FAM127B | ZC4H2 | ENSP00000375267 | ENSP00000363972 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | Zinc finger C4H2 domain-containing protein; Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation; Zinc fingers | 0.453 |
| FAM127B | ZNF606 | ENSP00000375267 | ENSP00000343617 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | Zinc finger protein 606; May act as a transcriptional repressor; Zinc fingers C2H2-type | 0.511 |
| MOSPD1 | FAM127B | ENSP00000359819 | ENSP00000375267 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to- mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | 0.540 |
| MOSPD1 | SLC10A3 | ENSP00000359819 | ENSP00000263512 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to- mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation | P3 protein; The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions; Solute carriers | 0.466 |
| MOSPD1 | ZC4H2 | ENSP00000359819 | ENSP00000363972 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to- mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation | Zinc finger C4H2 domain-containing protein; Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation; Zinc fingers | 0.569 |
| PEG10 | FAM127B | ENSP00000418944 | ENSP00000375267 | Retrotransposon-derived protein PEG10; Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5’-GCCTGTCTTT-3’ DNA sequence of the MB1 domain in the myelin basic protein (M [...] | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | 0.557 |
| PRRG1 | FAM127B | ENSP00000444278 | ENSP00000375267 | Transmembrane gamma-carboxyglutamic acid protein 1; Proline rich and Gla domain containing | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | 0.516 |
| RGAG1 | FAM127B | ENSP00000419786 | ENSP00000375267 | Retrotransposon Gag-like protein 9; Retrotransposon gag domain containing 1 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | 0.484 |
| RGAG1 | RGAG4 | ENSP00000419786 | ENSP00000476792 | Retrotransposon Gag-like protein 9; Retrotransposon gag domain containing 1 | Retrotransposon Gag-like protein 5; Retrotransposon gag domain containing 4 | 0.400 |
| RGAG4 | FAM127B | ENSP00000476792 | ENSP00000375267 | Retrotransposon Gag-like protein 5; Retrotransposon gag domain containing 4 | Retrotransposon Gag-like protein 8A; Family with sequence similarity 127, member B; Belongs to the FAM127 family | 0.641 |
| RGAG4 | RGAG1 | ENSP00000476792 | ENSP00000419786 | Retrotransposon Gag-like protein 5; Retrotransposon gag domain containing 4 | Retrotransposon Gag-like protein 9; Retrotransposon gag domain containing 1 | 0.400 |
