| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARHGAP25 | TMEM87A | ENSP00000386911 | ENSP00000374484 | Rho GTPase-activating protein 25; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state; Pleckstrin homology domain containing | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) | 0.584 |
| C11orf87 | DRAM2 | ENSP00000331581 | ENSP00000286692 | Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87 | DNA damage-regulated autophagy modulator protein 2; Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1; Belongs to the DRAM/TMEM150 family | 0.653 |
| C11orf87 | TMEM17 | ENSP00000331581 | ENSP00000335094 | Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87 | Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the TMEM17 family | 0.710 |
| C11orf87 | TMEM87A | ENSP00000331581 | ENSP00000374484 | Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87 | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) | 0.742 |
| CTDSPL2 | PNPT1 | ENSP00000260327 | ENSP00000400646 | CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases | Polyribonucleotide nucleotidyltransferase 1, mitochondrial; RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’-to-5’ direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double- stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. Required for correct processing and polyadenylation of mitochondrial mRNAs. Plays a role as a cytoplasmic RNA [...] | 0.541 |
| CTDSPL2 | TMEM87A | ENSP00000260327 | ENSP00000374484 | CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) | 0.651 |
| DRAM2 | C11orf87 | ENSP00000286692 | ENSP00000331581 | DNA damage-regulated autophagy modulator protein 2; Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1; Belongs to the DRAM/TMEM150 family | Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87 | 0.653 |
| DRAM2 | TMEM17 | ENSP00000286692 | ENSP00000335094 | DNA damage-regulated autophagy modulator protein 2; Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1; Belongs to the DRAM/TMEM150 family | Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the TMEM17 family | 0.465 |
| DRAM2 | TMEM87A | ENSP00000286692 | ENSP00000374484 | DNA damage-regulated autophagy modulator protein 2; Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1; Belongs to the DRAM/TMEM150 family | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) | 0.547 |
| GPR107 | GPR137C | ENSP00000361483 | ENSP00000315106 | Protein GPR107; Involved in Golgi-to-ER retrograde transport. Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins; Belongs to the LU7TM family | Integral membrane protein GPR137C; G protein-coupled receptor 137C | 0.649 |
| GPR107 | TMEM87A | ENSP00000361483 | ENSP00000374484 | Protein GPR107; Involved in Golgi-to-ER retrograde transport. Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins; Belongs to the LU7TM family | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) | 0.638 |
| GPR137C | GPR107 | ENSP00000315106 | ENSP00000361483 | Integral membrane protein GPR137C; G protein-coupled receptor 137C | Protein GPR107; Involved in Golgi-to-ER retrograde transport. Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins; Belongs to the LU7TM family | 0.649 |
| GPR137C | TMEM87A | ENSP00000315106 | ENSP00000374484 | Integral membrane protein GPR137C; G protein-coupled receptor 137C | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) | 0.479 |
| LRRC57 | TMEM87A | ENSP00000326817 | ENSP00000374484 | Leucine-rich repeat-containing protein 57; Leucine rich repeat containing 57 | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) | 0.480 |
| PNPT1 | CTDSPL2 | ENSP00000400646 | ENSP00000260327 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial; RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’-to-5’ direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double- stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. Required for correct processing and polyadenylation of mitochondrial mRNAs. Plays a role as a cytoplasmic RNA [...] | CTD small phosphatase-like protein 2; Probable phosphatase; CTD family phosphatases | 0.541 |
| PNPT1 | TMEM87A | ENSP00000400646 | ENSP00000374484 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial; RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’-to-5’ direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double- stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. Required for correct processing and polyadenylation of mitochondrial mRNAs. Plays a role as a cytoplasmic RNA [...] | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) | 0.526 |
| STX16 | TMEM87A | ENSP00000360183 | ENSP00000374484 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) | 0.549 |
| TMEM17 | C11orf87 | ENSP00000335094 | ENSP00000331581 | Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the TMEM17 family | Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87 | 0.710 |
| TMEM17 | DRAM2 | ENSP00000335094 | ENSP00000286692 | Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the TMEM17 family | DNA damage-regulated autophagy modulator protein 2; Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1; Belongs to the DRAM/TMEM150 family | 0.465 |
| TMEM17 | TMEM87A | ENSP00000335094 | ENSP00000374484 | Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the TMEM17 family | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) | 0.655 |
