node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C17orf67 | COL11A2 | ENSP00000380959 | ENSP00000363840 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Collagen alpha-2(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Collagens | 0.402 |
C17orf67 | FAM101A | ENSP00000380959 | ENSP00000374377 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | 0.615 |
C17orf67 | NUCKS1 | ENSP00000380959 | ENSP00000356110 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Nuclear casein kinase and cyclin dependent kinase substrate 1 | 0.598 |
C17orf67 | POC5 | ENSP00000380959 | ENSP00000410216 | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family | 0.580 |
CAAP1 | FAM101A | ENSP00000369431 | ENSP00000374377 | Caspase activity and apoptosis inhibitor 1; Anti-apoptotic protein that modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | 0.544 |
COL11A2 | C17orf67 | ENSP00000363840 | ENSP00000380959 | Collagen alpha-2(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Collagens | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | 0.402 |
COL11A2 | FAM101A | ENSP00000363840 | ENSP00000374377 | Collagen alpha-2(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Collagens | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | 0.505 |
COL11A2 | NUCKS1 | ENSP00000363840 | ENSP00000356110 | Collagen alpha-2(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Collagens | Nuclear casein kinase and cyclin dependent kinase substrate 1 | 0.418 |
COL11A2 | POC5 | ENSP00000363840 | ENSP00000410216 | Collagen alpha-2(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Collagens | Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family | 0.444 |
FAM101A | C17orf67 | ENSP00000374377 | ENSP00000380959 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | Uncharacterized protein C17orf67; Chromosome 17 open reading frame 67 | 0.615 |
FAM101A | CAAP1 | ENSP00000374377 | ENSP00000369431 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | Caspase activity and apoptosis inhibitor 1; Anti-apoptotic protein that modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop | 0.544 |
FAM101A | COL11A2 | ENSP00000374377 | ENSP00000363840 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | Collagen alpha-2(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Collagens | 0.505 |
FAM101A | FLNA | ENSP00000374377 | ENSP00000358866 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | Filamin-A; Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the de [...] | 0.716 |
FAM101A | FLNC | ENSP00000374377 | ENSP00000327145 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | Filamin-C; Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross- linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers | 0.591 |
FAM101A | HMG20A | ENSP00000374377 | ENSP00000371133 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | High mobility group protein 20A; Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity); Non-canonical high mobility group | 0.531 |
FAM101A | HNRNPM | ENSP00000374377 | ENSP00000325376 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | Heterogeneous nuclear ribonucleoprotein M; Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines | 0.544 |
FAM101A | NUCKS1 | ENSP00000374377 | ENSP00000356110 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | Nuclear casein kinase and cyclin dependent kinase substrate 1 | 0.548 |
FAM101A | POC5 | ENSP00000374377 | ENSP00000410216 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family | 0.591 |
FAM101A | TMEM106A | ENSP00000374377 | ENSP00000483246 | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | Transmembrane protein 106A; Belongs to the TMEM106 family | 0.551 |
FLNA | FAM101A | ENSP00000358866 | ENSP00000374377 | Filamin-A; Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the de [...] | Refilin-A; Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells | 0.716 |