• Version:
  • 11.0 [archived version]
STRINGSTRING
LUZP2 LUZP2 STK32A STK32A SCGB1C2 SCGB1C2 C22orf42 C22orf42 TMPRSS5 TMPRSS5 TMEM72 TMEM72 TMEM52B TMEM52B TMEM100 TMEM100 SMIM34B SMIM34B SUSD2 SUSD2 TMEM207 TMEM207
"TMEM72" - Transmembrane protein 72 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM72Transmembrane protein 72 (275 aa)    
Predicted Functional Partners:
LUZP2
Leucine zipper protein 2 (346 aa)
           
  0.624
SUSD2
Sushi domain-containing protein 2; May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest. May play a role in breast tumorigenesis; Sushi domain containing (822 aa)
     
   
  0.616
TMEM100
Transmembrane protein 100; Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open p [...] (134 aa)
           
  0.607
SMIM34B
annotation not available (139 aa)
           
  0.589
STK32A
Serine/threonine kinase 32A (407 aa)
           
  0.578
TMEM207
Transmembrane protein 207 (146 aa)
     
   
  0.573
C22orf42
Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42 (251 aa)
           
  0.571
TMEM52B
Transmembrane protein 52B (183 aa)
           
  0.570
TMPRSS5
Transmembrane protease serine 5; May play a role in hearing; Belongs to the peptidase S1 family (457 aa)
           
  0.552
SCGB1C2
Secretoglobin, family 1C, member 1-like precursor (95 aa)
           
  0.538
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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