node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CENPBD1 | DBNDD1 | ENSP00000393854 | ENSP00000457625 | CENPB DNA-binding domain-containing protein 1; Helix-turn-helix CENPB type domain containing | Dysbindin domain containing 1 | 0.556 |
CENPBD1 | PRDM7 | ENSP00000393854 | ENSP00000396732 | CENPB DNA-binding domain-containing protein 1; Helix-turn-helix CENPB type domain containing | Probable histone-lysine N-methyltransferase PRDM7; Probable histone methyltransferase; PR/SET domain family | 0.556 |
CENPBD1 | SPATA2L | ENSP00000393854 | ENSP00000289805 | CENPB DNA-binding domain-containing protein 1; Helix-turn-helix CENPB type domain containing | Spermatogenesis-associated protein 2-like protein; Spermatogenesis associated 2 like | 0.590 |
CENPBD1 | SPATA33 | ENSP00000393854 | ENSP00000462996 | CENPB DNA-binding domain-containing protein 1; Helix-turn-helix CENPB type domain containing | Spermatogenesis-associated protein 33; Spermatogenesis associated 33 | 0.642 |
CENPBD1 | VPS9D1 | ENSP00000393854 | ENSP00000374037 | CENPB DNA-binding domain-containing protein 1; Helix-turn-helix CENPB type domain containing | VPS9 domain containing 1 | 0.587 |
CENPBD1 | ZNF276 | ENSP00000393854 | ENSP00000415836 | CENPB DNA-binding domain-containing protein 1; Helix-turn-helix CENPB type domain containing | Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.591 |
DBNDD1 | CENPBD1 | ENSP00000457625 | ENSP00000393854 | Dysbindin domain containing 1 | CENPB DNA-binding domain-containing protein 1; Helix-turn-helix CENPB type domain containing | 0.556 |
DBNDD1 | PRDM7 | ENSP00000457625 | ENSP00000396732 | Dysbindin domain containing 1 | Probable histone-lysine N-methyltransferase PRDM7; Probable histone methyltransferase; PR/SET domain family | 0.442 |
DBNDD1 | SPATA2L | ENSP00000457625 | ENSP00000289805 | Dysbindin domain containing 1 | Spermatogenesis-associated protein 2-like protein; Spermatogenesis associated 2 like | 0.601 |
DBNDD1 | SPATA33 | ENSP00000457625 | ENSP00000462996 | Dysbindin domain containing 1 | Spermatogenesis-associated protein 33; Spermatogenesis associated 33 | 0.617 |
DBNDD1 | VPS9D1 | ENSP00000457625 | ENSP00000374037 | Dysbindin domain containing 1 | VPS9 domain containing 1 | 0.491 |
DBNDD1 | ZNF276 | ENSP00000457625 | ENSP00000415836 | Dysbindin domain containing 1 | Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.493 |
DTX2 | VPS9D1 | ENSP00000322885 | ENSP00000374037 | Probable E3 ubiquitin-protein ligase DTX2; Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity; Belongs to the Deltex family | VPS9 domain containing 1 | 0.511 |
GAPVD1 | RINL | ENSP00000377664 | ENSP00000467107 | GTPase-activating protein and VPS9 domain-containing protein 1; Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processes such as endocytosis, insulin receptor internalization or LC2A4/GLUT4 trafficking. Acts as a GEF for the Ras-related protein RAB31 by exchanging bound GDP for free GTP, leading to regulate LC2A4/GLUT4 trafficking. In the absence of insulin, it maintains RAB31 in an active state and promotes a futile cycle between LC2A4/GLUT4 storage vesicles and early endosomes, retaining LC2A4/GLUT4 inside th [...] | Ras and Rab interactor-like protein; Guanine nucleotide exchange factor (GEF) for RAB5A and RAB22A that activates RAB5A and RAB22A by exchanging bound GDP for free GTP. Plays a role in endocytosis via its role in activating Rab family members (By similarity); VPS9 domain containing | 0.413 |
GAPVD1 | VPS9D1 | ENSP00000377664 | ENSP00000374037 | GTPase-activating protein and VPS9 domain-containing protein 1; Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processes such as endocytosis, insulin receptor internalization or LC2A4/GLUT4 trafficking. Acts as a GEF for the Ras-related protein RAB31 by exchanging bound GDP for free GTP, leading to regulate LC2A4/GLUT4 trafficking. In the absence of insulin, it maintains RAB31 in an active state and promotes a futile cycle between LC2A4/GLUT4 storage vesicles and early endosomes, retaining LC2A4/GLUT4 inside th [...] | VPS9 domain containing 1 | 0.530 |
OBSL1 | VPS9D1 | ENSP00000385636 | ENSP00000374037 | Obscurin-like protein 1; Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Acts as a regulator of the Cul7-RING(FBXW8) ubiquitin-protein ligase, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain. Required to localize CUL7 to the Golgi apparatus in neurons; I-set domain containing | VPS9 domain containing 1 | 0.478 |
PRDM7 | CENPBD1 | ENSP00000396732 | ENSP00000393854 | Probable histone-lysine N-methyltransferase PRDM7; Probable histone methyltransferase; PR/SET domain family | CENPB DNA-binding domain-containing protein 1; Helix-turn-helix CENPB type domain containing | 0.556 |
PRDM7 | DBNDD1 | ENSP00000396732 | ENSP00000457625 | Probable histone-lysine N-methyltransferase PRDM7; Probable histone methyltransferase; PR/SET domain family | Dysbindin domain containing 1 | 0.442 |
PRDM7 | SPATA2L | ENSP00000396732 | ENSP00000289805 | Probable histone-lysine N-methyltransferase PRDM7; Probable histone methyltransferase; PR/SET domain family | Spermatogenesis-associated protein 2-like protein; Spermatogenesis associated 2 like | 0.511 |
PRDM7 | SPATA33 | ENSP00000396732 | ENSP00000462996 | Probable histone-lysine N-methyltransferase PRDM7; Probable histone methyltransferase; PR/SET domain family | Spermatogenesis-associated protein 33; Spermatogenesis associated 33 | 0.530 |