node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKMY1 | ANO7 | ENSP00000385887 | ENSP00000274979 | Ankyrin repeat and MYND domain containing 1 | Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions; Anoctamins | 0.629 |
ANKMY1 | C2orf54 | ENSP00000385887 | ENSP00000373586 | Ankyrin repeat and MYND domain containing 1 | Uncharacterized protein C2orf54; Chromosome 2 open reading frame 54 | 0.697 |
ANKMY1 | DTYMK | ENSP00000385887 | ENSP00000304802 | Ankyrin repeat and MYND domain containing 1 | Thymidylate kinase; Catalyzes the conversion of dTMP to dTDP; Belongs to the thymidylate kinase family | 0.641 |
ANKMY1 | FARP2 | ENSP00000385887 | ENSP00000264042 | Ankyrin repeat and MYND domain containing 1 | FERM, ARHGEF and pleckstrin domain-containing protein 2; Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity); FERM domain containing | 0.602 |
ANKMY1 | SEPT2 | ENSP00000385887 | ENSP00000479861 | Ankyrin repeat and MYND domain containing 1 | Septin-2; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the [...] | 0.608 |
ANKMY1 | SNED1 | ENSP00000385887 | ENSP00000308893 | Ankyrin repeat and MYND domain containing 1 | Sushi, nidogen and EGF-like domain-containing protein 1; Fibronectin type III domain containing | 0.622 |
ANKMY1 | STK25 | ENSP00000385887 | ENSP00000325748 | Ankyrin repeat and MYND domain containing 1 | Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration | 0.592 |
ANKMY1 | THAP4 | ENSP00000385887 | ENSP00000385006 | Ankyrin repeat and MYND domain containing 1 | THAP domain containing 4 | 0.709 |
ANO7 | ANKMY1 | ENSP00000274979 | ENSP00000385887 | Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions; Anoctamins | Ankyrin repeat and MYND domain containing 1 | 0.629 |
ANO7 | C2orf54 | ENSP00000274979 | ENSP00000373586 | Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions; Anoctamins | Uncharacterized protein C2orf54; Chromosome 2 open reading frame 54 | 0.631 |
ANO7 | DTYMK | ENSP00000274979 | ENSP00000304802 | Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions; Anoctamins | Thymidylate kinase; Catalyzes the conversion of dTMP to dTDP; Belongs to the thymidylate kinase family | 0.516 |
ANO7 | FARP2 | ENSP00000274979 | ENSP00000264042 | Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions; Anoctamins | FERM, ARHGEF and pleckstrin domain-containing protein 2; Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity); FERM domain containing | 0.479 |
ANO7 | SEPT2 | ENSP00000274979 | ENSP00000479861 | Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions; Anoctamins | Septin-2; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the [...] | 0.505 |
ANO7 | SNED1 | ENSP00000274979 | ENSP00000308893 | Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions; Anoctamins | Sushi, nidogen and EGF-like domain-containing protein 1; Fibronectin type III domain containing | 0.514 |
ANO7 | STK25 | ENSP00000274979 | ENSP00000325748 | Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions; Anoctamins | Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration | 0.463 |
ANO7 | THAP4 | ENSP00000274979 | ENSP00000385006 | Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions; Anoctamins | THAP domain containing 4 | 0.643 |
C2orf54 | ANKMY1 | ENSP00000373586 | ENSP00000385887 | Uncharacterized protein C2orf54; Chromosome 2 open reading frame 54 | Ankyrin repeat and MYND domain containing 1 | 0.697 |
C2orf54 | ANO7 | ENSP00000373586 | ENSP00000274979 | Uncharacterized protein C2orf54; Chromosome 2 open reading frame 54 | Anoctamin-7; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions; Anoctamins | 0.631 |
C2orf54 | DTYMK | ENSP00000373586 | ENSP00000304802 | Uncharacterized protein C2orf54; Chromosome 2 open reading frame 54 | Thymidylate kinase; Catalyzes the conversion of dTMP to dTDP; Belongs to the thymidylate kinase family | 0.648 |
C2orf54 | FAM171B | ENSP00000373586 | ENSP00000304108 | Uncharacterized protein C2orf54; Chromosome 2 open reading frame 54 | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family | 0.594 |