| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DZIP1L | LMCD1 | ENSP00000332148 | ENSP00000157600 | Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family | LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway; LIM domain containing | 0.414 |
| DZIP1L | LRRC58 | ENSP00000332148 | ENSP00000295628 | Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family | Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58 | 0.585 |
| DZIP1L | TOPAZ1 | ENSP00000332148 | ENSP00000310303 | Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family | Testis- and ovary-specific PAZ domain-containing protein 1; Testis and ovary specific PAZ domain containing 1 | 0.560 |
| DZIP1L | ZNF860 | ENSP00000332148 | ENSP00000373274 | Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family | Zinc finger protein 860; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.511 |
| FAM19A4 | LRRC58 | ENSP00000295569 | ENSP00000295628 | Protein FAM19A4; Family with sequence similarity 19 member A4, C-C motif chemokine like | Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58 | 0.551 |
| FAM19A4 | OSBPL10 | ENSP00000295569 | ENSP00000379804 | Protein FAM19A4; Family with sequence similarity 19 member A4, C-C motif chemokine like | Oxysterol-binding protein-related protein 10; Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (Probable). Plays a role in negative regulation of lipid biosynthesis. Negatively regulates APOB secretion from hepatocytes. Binds cholesterol and acidic phospholipids. Also binds 25-hydroxycholesterol. Bin [...] | 0.420 |
| FAM19A4 | TOPAZ1 | ENSP00000295569 | ENSP00000310303 | Protein FAM19A4; Family with sequence similarity 19 member A4, C-C motif chemokine like | Testis- and ovary-specific PAZ domain-containing protein 1; Testis and ovary specific PAZ domain containing 1 | 0.428 |
| FAM19A4 | ZNF860 | ENSP00000295569 | ENSP00000373274 | Protein FAM19A4; Family with sequence similarity 19 member A4, C-C motif chemokine like | Zinc finger protein 860; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.553 |
| HHIPL1 | ZNF860 | ENSP00000330601 | ENSP00000373274 | HHIP-like protein 1; Scavenger receptor cysteine rich domain containing | Zinc finger protein 860; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.473 |
| KIAA1328 | ZNF860 | ENSP00000280020 | ENSP00000373274 | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes | Zinc finger protein 860; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.473 |
| LMCD1 | DZIP1L | ENSP00000157600 | ENSP00000332148 | LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway; LIM domain containing | Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family | 0.414 |
| LMCD1 | LRRC58 | ENSP00000157600 | ENSP00000295628 | LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway; LIM domain containing | Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58 | 0.499 |
| LMCD1 | SETD5 | ENSP00000157600 | ENSP00000385852 | LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway; LIM domain containing | SET domain-containing protein 5; Probable transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Acts as a regulator of histone acetylation during gene transcription; SET domain containing | 0.450 |
| LMCD1 | TOPAZ1 | ENSP00000157600 | ENSP00000310303 | LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway; LIM domain containing | Testis- and ovary-specific PAZ domain-containing protein 1; Testis and ovary specific PAZ domain containing 1 | 0.443 |
| LMCD1 | ZNF860 | ENSP00000157600 | ENSP00000373274 | LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway; LIM domain containing | Zinc finger protein 860; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.489 |
| LRRC58 | DZIP1L | ENSP00000295628 | ENSP00000332148 | Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58 | Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family | 0.585 |
| LRRC58 | FAM19A4 | ENSP00000295628 | ENSP00000295569 | Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58 | Protein FAM19A4; Family with sequence similarity 19 member A4, C-C motif chemokine like | 0.551 |
| LRRC58 | LMCD1 | ENSP00000295628 | ENSP00000157600 | Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58 | LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway; LIM domain containing | 0.499 |
| LRRC58 | OSBPL10 | ENSP00000295628 | ENSP00000379804 | Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58 | Oxysterol-binding protein-related protein 10; Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (Probable). Plays a role in negative regulation of lipid biosynthesis. Negatively regulates APOB secretion from hepatocytes. Binds cholesterol and acidic phospholipids. Also binds 25-hydroxycholesterol. Bin [...] | 0.535 |
| LRRC58 | SETD5 | ENSP00000295628 | ENSP00000385852 | Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58 | SET domain-containing protein 5; Probable transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Acts as a regulator of histone acetylation during gene transcription; SET domain containing | 0.487 |
