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STRINGSTRING
TP53TG5 TP53TG5 C16orf90 C16orf90 RPS6KA2 RPS6KA2 GTF2IRD1 GTF2IRD1 RPS6KA3 RPS6KA3 ZMYM5 ZMYM5 N6AMT2 N6AMT2 ZDHHC20 ZDHHC20 SKA3 SKA3 ZNF557 ZNF557 PSPC1 PSPC1
"ZMYM5" - Zinc finger MYM-type protein 5 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZMYM5Zinc finger MYM-type protein 5; Functions as a transcriptional regulator; Zinc fingers MYM-type (382 aa)    
Predicted Functional Partners:
GTF2IRD1
General transcription factor II-I repeat domain-containing protein 1; May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity) (976 aa)
        
 
  0.617
ZDHHC20
Probable palmitoyltransferase ZDHHC20; Zinc finger DHHC-type containing 20; Belongs to the DHHC palmitoyltransferase family (354 aa)
      
   
  0.548
C16orf90
Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90 (182 aa)
            
  0.542
ZNF557
Zinc finger protein 557; May be involved in transcriptional regulation; Zinc fingers C2H2-type (430 aa)
            
  0.519
RPS6KA3
Ribosomal protein S6 kinase alpha-3; Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1 and histone H3 at ’Ser-10’, which results in the subsequ [...] (740 aa)
        
      0.516
TP53TG5
TP53-target gene 5 protein; May play a significant role in p53/TP53-mediating signaling pathway (290 aa)
            
  0.473
SKA3
Spindle and kinetochore-associated protein 3; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization. Affinity for microtubules is synergistically enhanced in the p [...] (412 aa)
            
  0.472
RPS6KA2
Ribosomal protein S6 kinase alpha-2; Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells; Mitogen-activated protein kinase-activated protein kinases (741 aa)
        
      0.455
PSPC1
Paraspeckle component 1; Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line (By similarity). Binds to poly(A), poly(G) and poly(U) RNA homopolymers. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Together with NONO, required for the formation of nuclear paraspeckles. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 pho [...] (523 aa)
      
   
  0.441
N6AMT2
EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-79’ (214 aa)
            
  0.440
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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