• Version:
  • 11.0 [archived version]
STRINGSTRING
DEFB124 DEFB124 DEFB116 DEFB116 DEFB127 DEFB127 DEFB126 DEFB126 DEFB125 DEFB125 DEFB134 DEFB134 DEFB112 DEFB112 DEFB129 DEFB129 DEFB132 DEFB132 DEFB135 DEFB135 DEFB128 DEFB128
"DEFB125" - Beta-defensin 125 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB125Beta-defensin 125; Has antibacterial activity; Defensins, beta (156 aa)    
Predicted Functional Partners:
DEFB128
Beta-defensin 128; Has antibacterial activity; Defensins, beta (93 aa)
      
 
  0.983
DEFB129
Beta-defensin 129; Has antibacterial activity; Defensins, beta (183 aa)
      
 
  0.982
DEFB135
Beta-defensin 135; Has antibacterial activity; Defensins, beta (77 aa)
      
 
  0.979
DEFB127
Beta-defensin 127; Has antibacterial activity; Defensins, beta (99 aa)
      
 
  0.978
DEFB124
Beta-defensin 124; Has antibacterial activity; Defensins, beta (71 aa)
          
  0.978
DEFB132
Beta-defensin 132; Has antibacterial activity; Defensins, beta (95 aa)
          
  0.965
DEFB126
Beta-defensin 126; Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other s [...] (111 aa)
      
 
  0.963
DEFB116
Beta-defensin 116; Has antibacterial activity; Defensins, beta (102 aa)
      
 
  0.961
DEFB134
Beta-defensin 134; Has antibacterial activity; Defensins, beta (66 aa)
          
  0.961
DEFB112
Beta-defensin 112; Has antibacterial activity; Defensins, beta (113 aa)
      
 
  0.955
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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