| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANKEF1 | FAM96B | ENSP00000367631 | ENSP00000387471 | Ankyrin repeat and EF-hand domain containing 1 | Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family | 0.541 |
| ANKEF1 | GTPBP10 | ENSP00000367631 | ENSP00000222511 | Ankyrin repeat and EF-hand domain containing 1 | GTP-binding protein 10; May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | 0.685 |
| ANKEF1 | ZG16B | ENSP00000367631 | ENSP00000371715 | Ankyrin repeat and EF-hand domain containing 1 | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.620 |
| CXCR4 | ZG16B | ENSP00000386884 | ENSP00000371715 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar developme [...] | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.428 |
| DUSP15 | ZG16B | ENSP00000341658 | ENSP00000371715 | Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.495 |
| FAM96B | ANKEF1 | ENSP00000387471 | ENSP00000367631 | Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family | Ankyrin repeat and EF-hand domain containing 1 | 0.541 |
| FAM96B | GTPBP10 | ENSP00000387471 | ENSP00000222511 | Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family | GTP-binding protein 10; May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | 0.562 |
| FAM96B | ZG16B | ENSP00000387471 | ENSP00000371715 | Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.485 |
| GTPBP10 | ANKEF1 | ENSP00000222511 | ENSP00000367631 | GTP-binding protein 10; May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | Ankyrin repeat and EF-hand domain containing 1 | 0.685 |
| GTPBP10 | FAM96B | ENSP00000222511 | ENSP00000387471 | GTP-binding protein 10; May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family | 0.562 |
| GTPBP10 | ZG16B | ENSP00000222511 | ENSP00000371715 | GTP-binding protein 10; May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.682 |
| LYZ | PRR4 | ENSP00000261267 | ENSP00000228811 | Lysozyme C; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte- macrophage system and enhance the activity of immunoagents; Lysozymes, c-type | Proline-rich protein 4; Proline rich 4 | 0.424 |
| LYZ | ZG16B | ENSP00000261267 | ENSP00000371715 | Lysozyme C; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte- macrophage system and enhance the activity of immunoagents; Lysozymes, c-type | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.510 |
| PRR4 | LYZ | ENSP00000228811 | ENSP00000261267 | Proline-rich protein 4; Proline rich 4 | Lysozyme C; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte- macrophage system and enhance the activity of immunoagents; Lysozymes, c-type | 0.424 |
| PRR4 | ZG16B | ENSP00000228811 | ENSP00000371715 | Proline-rich protein 4; Proline rich 4 | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.536 |
| S100PBP | ZG16B | ENSP00000362574 | ENSP00000371715 | S100P binding protein | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.613 |
| UBAC1 | ZG16B | ENSP00000360821 | ENSP00000371715 | Ubiquitin-associated domain-containing protein 1; Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.728 |
| ZBTB42 | ZG16B | ENSP00000409107 | ENSP00000371715 | Zinc finger and BTB domain-containing protein 42; Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes; BTB domain containing | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.491 |
| ZG16B | ANKEF1 | ENSP00000371715 | ENSP00000367631 | Zymogen granule protein 16B; Belongs to the jacalin lectin family | Ankyrin repeat and EF-hand domain containing 1 | 0.620 |
| ZG16B | CXCR4 | ENSP00000371715 | ENSP00000386884 | Zymogen granule protein 16B; Belongs to the jacalin lectin family | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar developme [...] | 0.428 |
