| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C1QTNF9B | CIART | ENSP00000371572 | ENSP00000290363 | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | Circadian-associated transcriptional repressor; Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptional repressors- CRY1, CRY2 and BHLHE41. In a histone deacetylase-dependent manner represses the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Abrogates the interaction of ARNTL/BMAL1 with the transcriptional coactivator CREBBP and can repress the histone acetyl-transferase activity of the CLOCK-ARNTL/BMAL1 heterodimer, reducing histone acetylation of its target genes. R [...] | 0.410 |
| C1QTNF9B | CLEC18A | ENSP00000371572 | ENSP00000484176 | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | C-type lectin domain family 18 member A; Binds polysaccharides in a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans; C-type lectin domain containing | 0.475 |
| C1QTNF9B | CLEC18C | ENSP00000371572 | ENSP00000477846 | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | C-type lectin domain family 18 member C; Binds polysaccharidesin a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans; C-type lectin domain containing | 0.510 |
| C1QTNF9B | CYP27C1 | ENSP00000371572 | ENSP00000334128 | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | Cytochrome P450 27C1; Catalyzes the conversion of all-trans retinol (also called vitamin A1, the precursor of 11-cis retinal) to 3,4- didehydroretinol (also called vitamin A2, the precursor of 11-cis 3,4-didehydroretinal). Also acts on all-trans retinal and all- trans retinoic acid; Cytochrome P450 family 27 | 0.511 |
| C1QTNF9B | MIPEP | ENSP00000371572 | ENSP00000371607 | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size; M3 metallopeptidases | 0.691 |
| C1QTNF9B | PPP1R21 | ENSP00000371572 | ENSP00000294952 | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | Protein phosphatase 1 regulatory subunit 21 | 0.443 |
| C1QTNF9B | PPP1R3B | ENSP00000371572 | ENSP00000308318 | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | Protein phosphatase 1 regulatory subunit 3B; Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated gl [...] | 0.476 |
| C1QTNF9B | SNTB1 | ENSP00000371572 | ENSP00000378965 | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | Beta-1-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex; Belongs to the syntrophin family | 0.540 |
| CIART | C1QTNF9B | ENSP00000290363 | ENSP00000371572 | Circadian-associated transcriptional repressor; Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptional repressors- CRY1, CRY2 and BHLHE41. In a histone deacetylase-dependent manner represses the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Abrogates the interaction of ARNTL/BMAL1 with the transcriptional coactivator CREBBP and can repress the histone acetyl-transferase activity of the CLOCK-ARNTL/BMAL1 heterodimer, reducing histone acetylation of its target genes. R [...] | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | 0.410 |
| CLEC18A | C1QTNF9B | ENSP00000484176 | ENSP00000371572 | C-type lectin domain family 18 member A; Binds polysaccharides in a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans; C-type lectin domain containing | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | 0.475 |
| CLEC18C | C1QTNF9B | ENSP00000477846 | ENSP00000371572 | C-type lectin domain family 18 member C; Binds polysaccharidesin a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans; C-type lectin domain containing | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | 0.510 |
| CYP27C1 | C1QTNF9B | ENSP00000334128 | ENSP00000371572 | Cytochrome P450 27C1; Catalyzes the conversion of all-trans retinol (also called vitamin A1, the precursor of 11-cis retinal) to 3,4- didehydroretinol (also called vitamin A2, the precursor of 11-cis 3,4-didehydroretinal). Also acts on all-trans retinal and all- trans retinoic acid; Cytochrome P450 family 27 | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | 0.511 |
| MIPEP | C1QTNF9B | ENSP00000371607 | ENSP00000371572 | Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size; M3 metallopeptidases | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | 0.691 |
| MIPEP | PPP1R3B | ENSP00000371607 | ENSP00000308318 | Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size; M3 metallopeptidases | Protein phosphatase 1 regulatory subunit 3B; Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated gl [...] | 0.543 |
| MIPEP | SNTB1 | ENSP00000371607 | ENSP00000378965 | Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size; M3 metallopeptidases | Beta-1-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex; Belongs to the syntrophin family | 0.527 |
| PPP1R21 | C1QTNF9B | ENSP00000294952 | ENSP00000371572 | Protein phosphatase 1 regulatory subunit 21 | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | 0.443 |
| PPP1R3B | C1QTNF9B | ENSP00000308318 | ENSP00000371572 | Protein phosphatase 1 regulatory subunit 3B; Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated gl [...] | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | 0.476 |
| PPP1R3B | MIPEP | ENSP00000308318 | ENSP00000371607 | Protein phosphatase 1 regulatory subunit 3B; Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated gl [...] | Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size; M3 metallopeptidases | 0.543 |
| PPP1R3B | SNTB1 | ENSP00000308318 | ENSP00000378965 | Protein phosphatase 1 regulatory subunit 3B; Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated gl [...] | Beta-1-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex; Belongs to the syntrophin family | 0.529 |
| SNTB1 | C1QTNF9B | ENSP00000378965 | ENSP00000371572 | Beta-1-syntrophin; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex; Belongs to the syntrophin family | Complement C1q and tumor necrosis factor-related protein 9B; C1q and TNF related 9B | 0.540 |
