C1QTNF3 protein (human) - STRING database

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C1QTNF3

Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3 (319 aa)

Predicted Functional Partners:

MALL

0.747

SERPINC1

0.669

HSPB3

0.577

NPHP1

0.539

F2

0.533

MAL

0.531

FAM132A

0.498

LYPD2

0.455

TMEM216

0.454

CTXN3

0.448

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1QTNF3	CTXN3	ENSP00000371497	ENSP00000368758	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	Cortexin-3; Cortexin 3; Belongs to the cortexin family	0.448
C1QTNF3	F2	ENSP00000371497	ENSP00000308541	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family	0.533
C1QTNF3	FAM132A	ENSP00000371497	ENSP00000329137	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	Adipolin; Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue	0.498
C1QTNF3	HSPB3	ENSP00000371497	ENSP00000303394	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	Heat shock protein beta-3; Inhibitor of actin polymerization; Small heat shock proteins	0.577
C1QTNF3	LYPD2	ENSP00000371497	ENSP00000352163	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	LY6/PLAUR domain containing 2	0.455
C1QTNF3	MAL	ENSP00000371497	ENSP00000310880	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	Myelin and lymphocyte protein; Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function; Belongs to the MAL family	0.531
C1QTNF3	MALL	ENSP00000371497	ENSP00000272462	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	MAL-like protein; Mal, T cell differentiation protein like; Belongs to the MAL family	0.747
C1QTNF3	NPHP1	ENSP00000371497	ENSP00000313169	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	Nephrocystin-1; Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity). Seems to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assembly. Required for normal retina development. In connecting photorec [...]	0.539
C1QTNF3	SERPINC1	ENSP00000371497	ENSP00000356671	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin; Serpin peptidase inhibitors	0.669
C1QTNF3	TMEM216	ENSP00000371497	ENSP00000440638	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	Transmembrane protein 216; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition	0.454
CTXN3	C1QTNF3	ENSP00000368758	ENSP00000371497	Cortexin-3; Cortexin 3; Belongs to the cortexin family	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	0.448
F2	C1QTNF3	ENSP00000308541	ENSP00000371497	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	0.533
F2	SERPINC1	ENSP00000308541	ENSP00000356671	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family	Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin; Serpin peptidase inhibitors	0.999
FAM132A	C1QTNF3	ENSP00000329137	ENSP00000371497	Adipolin; Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	0.498
HSPB3	C1QTNF3	ENSP00000303394	ENSP00000371497	Heat shock protein beta-3; Inhibitor of actin polymerization; Small heat shock proteins	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	0.577
LYPD2	C1QTNF3	ENSP00000352163	ENSP00000371497	LY6/PLAUR domain containing 2	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	0.455
MAL	C1QTNF3	ENSP00000310880	ENSP00000371497	Myelin and lymphocyte protein; Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function; Belongs to the MAL family	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	0.531
MAL	NPHP1	ENSP00000310880	ENSP00000313169	Myelin and lymphocyte protein; Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function; Belongs to the MAL family	Nephrocystin-1; Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity). Seems to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assembly. Required for normal retina development. In connecting photorec [...]	0.615
MALL	C1QTNF3	ENSP00000272462	ENSP00000371497	MAL-like protein; Mal, T cell differentiation protein like; Belongs to the MAL family	Complement C1q tumor necrosis factor-related protein 3; C1q and TNF related 3	0.747
MALL	NPHP1	ENSP00000272462	ENSP00000313169	MAL-like protein; Mal, T cell differentiation protein like; Belongs to the MAL family	Nephrocystin-1; Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity). Seems to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assembly. Required for normal retina development. In connecting photorec [...]	0.714

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