• Version:
  • 11.0 [archived version]
STRINGSTRING
TLDC1 TLDC1 RNF222 RNF222 MED31 MED31 DUS3L DUS3L ZZEF1 ZZEF1 FBXL17 FBXL17 ZNHIT3 ZNHIT3 ZBTB11 ZBTB11 WDR54 WDR54 IMMP1L IMMP1L EVA1B EVA1B
"ZZEF1" - Zinc finger ZZ-type and EF-hand domain containing 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZZEF1Zinc finger ZZ-type and EF-hand domain containing 1 (2961 aa)    
Predicted Functional Partners:
WDR54
WD repeat-containing protein 54; WD repeat domain containing (334 aa)
           
  0.733
MED31
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (131 aa)
     
   
  0.722
FBXL17
F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins (701 aa)
     
   
  0.698
EVA1B
Eva-1 homolog B; Belongs to the EVA1 family (165 aa)
           
  0.665
TLDC1
TLD domain-containing protein 1; TBC/LysM-associated domain containing 1 (456 aa)
           
  0.658
RNF222
Ring finger protein 222 (220 aa)
           
  0.642
IMMP1L
Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO (166 aa)
     
   
  0.631
ZBTB11
Zinc finger and BTB domain-containing protein 11; May be involved in transcriptional regulation; BTB domain containing (1053 aa)
     
   
  0.607
DUS3L
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (650 aa)
     
   
  0.593
ZNHIT3
Zinc finger HIT-type containing 3 (155 aa)
           
  0.581
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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