node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANPEP | GCLC | ENSP00000300060 | ENSP00000229416 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | Glutamate-cysteine ligase catalytic subunit | 0.938 |
ANPEP | GGT6 | ENSP00000300060 | ENSP00000370962 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | Glutathione hydrolase 6; Cleaves glutathione conjugates; Gamma-glutamyltransferases | 0.952 |
ANPEP | GSS | ENSP00000300060 | ENSP00000216951 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family | 0.903 |
ANPEP | LAP3 | ENSP00000300060 | ENSP00000226299 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides; Belongs to the peptidase M17 family | 0.939 |
CSAD | GAD1 | ENSP00000267085 | ENSP00000350928 | Cysteine sulfinic acid decarboxylase | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | 0.807 |
CSAD | GAD2 | ENSP00000267085 | ENSP00000365437 | Cysteine sulfinic acid decarboxylase | Glutamate decarboxylase 2; Catalyzes the production of GABA | 0.837 |
CSAD | GGT6 | ENSP00000267085 | ENSP00000370962 | Cysteine sulfinic acid decarboxylase | Glutathione hydrolase 6; Cleaves glutathione conjugates; Gamma-glutamyltransferases | 0.911 |
GAD1 | CSAD | ENSP00000350928 | ENSP00000267085 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | Cysteine sulfinic acid decarboxylase | 0.807 |
GAD1 | GAD2 | ENSP00000350928 | ENSP00000365437 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | Glutamate decarboxylase 2; Catalyzes the production of GABA | 0.956 |
GAD1 | GCLC | ENSP00000350928 | ENSP00000229416 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | Glutamate-cysteine ligase catalytic subunit | 0.823 |
GAD1 | GGT6 | ENSP00000350928 | ENSP00000370962 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | Glutathione hydrolase 6; Cleaves glutathione conjugates; Gamma-glutamyltransferases | 0.913 |
GAD1 | OPLAH | ENSP00000350928 | ENSP00000480476 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | 5-oxoprolinase; Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate | 0.802 |
GAD2 | CSAD | ENSP00000365437 | ENSP00000267085 | Glutamate decarboxylase 2; Catalyzes the production of GABA | Cysteine sulfinic acid decarboxylase | 0.837 |
GAD2 | GAD1 | ENSP00000365437 | ENSP00000350928 | Glutamate decarboxylase 2; Catalyzes the production of GABA | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | 0.956 |
GAD2 | GCLC | ENSP00000365437 | ENSP00000229416 | Glutamate decarboxylase 2; Catalyzes the production of GABA | Glutamate-cysteine ligase catalytic subunit | 0.810 |
GAD2 | GGT6 | ENSP00000365437 | ENSP00000370962 | Glutamate decarboxylase 2; Catalyzes the production of GABA | Glutathione hydrolase 6; Cleaves glutathione conjugates; Gamma-glutamyltransferases | 0.914 |
GAD2 | OPLAH | ENSP00000365437 | ENSP00000480476 | Glutamate decarboxylase 2; Catalyzes the production of GABA | 5-oxoprolinase; Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate | 0.802 |
GCLC | ANPEP | ENSP00000229416 | ENSP00000300060 | Glutamate-cysteine ligase catalytic subunit | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | 0.938 |
GCLC | GAD1 | ENSP00000229416 | ENSP00000350928 | Glutamate-cysteine ligase catalytic subunit | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family | 0.823 |
GCLC | GAD2 | ENSP00000229416 | ENSP00000365437 | Glutamate-cysteine ligase catalytic subunit | Glutamate decarboxylase 2; Catalyzes the production of GABA | 0.810 |