• Version:
  • 11.0 [archived version]
STRINGSTRING
PPAP2C PPAP2C OR4F17 OR4F17 MIER2 MIER2 ZNF557 ZNF557 MBD3L4 MBD3L4 MTA3 MTA3 GATAD2A GATAD2A GATAD2B GATAD2B
"MBD3L4" - methyl-CpG binding domain protein 3 like 4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MBD3L4methyl-CpG binding domain protein 3 like 4 (208 aa)    
Predicted Functional Partners:
ZNF557
Zinc finger protein 557; May be involved in transcriptional regulation; Zinc fingers C2H2-type (430 aa)
        
 
  0.674
OR4F17
Olfactory receptor 4F17; Odorant receptor; Olfactory receptors, family 4 (305 aa)
            
  0.670
MIER2
Mesoderm induction early response protein 2; Transcriptional repressor; Myb/SANT domain containing (545 aa)
            
  0.562
GATAD2B
Transcriptional repressor p66-beta; Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development; GATA zinc finger domain containing (593 aa)
        
 
  0.460
GATAD2A
Transcriptional repressor p66-alpha; Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B; GATA zinc finger domain containing (633 aa)
        
 
  0.452
PPAP2C
Phospholipid phosphatase 2; Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P; Belongs to the PA-phosphatase related phosphoesterase family (309 aa)
            
  0.447
MTA3
Metastasis-associated protein MTA3; Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6; GATA zinc finger domain containing (537 aa)
        
 
  0.402
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >