NOXRED1 protein (human) - STRING database

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Score

NOXRED1

NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase (359 aa)

Predicted Functional Partners:

ALDH18A1

0.798

C14orf178

0.765

SAMD15

0.731

TMED8

0.680

ADCK1

0.668

ISM2

0.574

VIPAS39

0.572

SLIRP

0.516

CSNK1A1

0.509

MPZL1

0.507

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCK1	C14orf178	ENSP00000238561	ENSP00000348145	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	0.585
ADCK1	NOXRED1	ENSP00000238561	ENSP00000370215	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	0.668
ADCK1	SAMD15	ENSP00000238561	ENSP00000216471	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	Sterile alpha motif domain containing 15	0.556
ADCK1	TMED8	ENSP00000238561	ENSP00000216468	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.497
ALDH18A1	NOXRED1	ENSP00000360268	ENSP00000370215	Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	0.798
C14orf178	ADCK1	ENSP00000348145	ENSP00000238561	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	0.585
C14orf178	ISM2	ENSP00000348145	ENSP00000341490	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	Isthmin-2; Isthmin 2	0.530
C14orf178	NOXRED1	ENSP00000348145	ENSP00000370215	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	0.765
C14orf178	SAMD15	ENSP00000348145	ENSP00000216471	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	Sterile alpha motif domain containing 15	0.679
C14orf178	SLIRP	ENSP00000348145	ENSP00000450909	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	SRA stem-loop-interacting RNA-binding protein, mitochondrial; RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation	0.447
C14orf178	TMED8	ENSP00000348145	ENSP00000216468	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.669
C14orf178	VIPAS39	ENSP00000348145	ENSP00000452181	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	Spermatogenesis-defective protein 39 homolog; Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B-VIPAS39 complex may play a role in the apical RAB11A- dependent recycling pathway and in the maintenance of the apical- basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of VPS33B. May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or ind [...]	0.530
CSNK1A1	NOXRED1	ENSP00000421689	ENSP00000370215	Casein kinase I isoform alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at ’Ser-45’. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	0.509
ISM2	C14orf178	ENSP00000341490	ENSP00000348145	Isthmin-2; Isthmin 2	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	0.530
ISM2	NOXRED1	ENSP00000341490	ENSP00000370215	Isthmin-2; Isthmin 2	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	0.574
ISM2	SAMD15	ENSP00000341490	ENSP00000216471	Isthmin-2; Isthmin 2	Sterile alpha motif domain containing 15	0.474
ISM2	TMED8	ENSP00000341490	ENSP00000216468	Isthmin-2; Isthmin 2	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.424
MPZL1	NOXRED1	ENSP00000352513	ENSP00000370215	Myelin protein zero-like protein 1; Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine- protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility; V-set dom [...]	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	0.507
NOXRED1	ADCK1	ENSP00000370215	ENSP00000238561	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	0.668
NOXRED1	ALDH18A1	ENSP00000370215	ENSP00000360268	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine	0.798

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