node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDKN1C | KCNQ1 | ENSP00000413720 | ENSP00000155840 | Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life; Belongs to the CDI family | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta- adrenergic receptor stimulation participates in cardiac [...] | 0.675 |
CDKN1C | NAP1L4 | ENSP00000413720 | ENSP00000369915 | Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life; Belongs to the CDI family | Nucleosome assembly protein 1-like 4; Acts as histone chaperone in nucleosome assembly; Belongs to the nucleosome assembly protein (NAP) family | 0.515 |
CDKN1C | PHLDA2 | ENSP00000413720 | ENSP00000319231 | Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life; Belongs to the CDI family | Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity); Belongs to the PHLDA2 family | 0.719 |
CDKN1C | SGCE | ENSP00000413720 | ENSP00000398930 | Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life; Belongs to the CDI family | Epsilon-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix | 0.468 |
CDKN1C | SLC22A18 | ENSP00000413720 | ENSP00000369948 | Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life; Belongs to the CDI family | Solute carrier family 22 member 18; May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney; Solute carriers | 0.669 |
CDKN1C | SLC22A18AS | ENSP00000413720 | ENSP00000433282 | Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life; Belongs to the CDI family | Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein; Solute carrier family 22 member 18 antisense | 0.640 |
CDKN1C | TSSC4 | ENSP00000413720 | ENSP00000331087 | Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life; Belongs to the CDI family | Protein TSSC4; Tumor suppressing subtransferable candidate 4 | 0.580 |
KCNQ1 | CDKN1C | ENSP00000155840 | ENSP00000413720 | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta- adrenergic receptor stimulation participates in cardiac [...] | Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life; Belongs to the CDI family | 0.675 |
KCNQ1 | NAP1L4 | ENSP00000155840 | ENSP00000369915 | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta- adrenergic receptor stimulation participates in cardiac [...] | Nucleosome assembly protein 1-like 4; Acts as histone chaperone in nucleosome assembly; Belongs to the nucleosome assembly protein (NAP) family | 0.503 |
KCNQ1 | PHLDA2 | ENSP00000155840 | ENSP00000319231 | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta- adrenergic receptor stimulation participates in cardiac [...] | Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity); Belongs to the PHLDA2 family | 0.756 |
KCNQ1 | SLC22A18 | ENSP00000155840 | ENSP00000369948 | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta- adrenergic receptor stimulation participates in cardiac [...] | Solute carrier family 22 member 18; May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney; Solute carriers | 0.669 |
KCNQ1 | SLC22A18AS | ENSP00000155840 | ENSP00000433282 | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta- adrenergic receptor stimulation participates in cardiac [...] | Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein; Solute carrier family 22 member 18 antisense | 0.720 |
KCNQ1 | TSSC4 | ENSP00000155840 | ENSP00000331087 | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta- adrenergic receptor stimulation participates in cardiac [...] | Protein TSSC4; Tumor suppressing subtransferable candidate 4 | 0.641 |
NAP1L4 | CDKN1C | ENSP00000369915 | ENSP00000413720 | Nucleosome assembly protein 1-like 4; Acts as histone chaperone in nucleosome assembly; Belongs to the nucleosome assembly protein (NAP) family | Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life; Belongs to the CDI family | 0.515 |
NAP1L4 | KCNQ1 | ENSP00000369915 | ENSP00000155840 | Nucleosome assembly protein 1-like 4; Acts as histone chaperone in nucleosome assembly; Belongs to the nucleosome assembly protein (NAP) family | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta- adrenergic receptor stimulation participates in cardiac [...] | 0.503 |
NAP1L4 | PHLDA2 | ENSP00000369915 | ENSP00000319231 | Nucleosome assembly protein 1-like 4; Acts as histone chaperone in nucleosome assembly; Belongs to the nucleosome assembly protein (NAP) family | Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity); Belongs to the PHLDA2 family | 0.773 |
NAP1L4 | SLC22A18 | ENSP00000369915 | ENSP00000369948 | Nucleosome assembly protein 1-like 4; Acts as histone chaperone in nucleosome assembly; Belongs to the nucleosome assembly protein (NAP) family | Solute carrier family 22 member 18; May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney; Solute carriers | 0.699 |
NAP1L4 | SLC22A18AS | ENSP00000369915 | ENSP00000433282 | Nucleosome assembly protein 1-like 4; Acts as histone chaperone in nucleosome assembly; Belongs to the nucleosome assembly protein (NAP) family | Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein; Solute carrier family 22 member 18 antisense | 0.560 |
NAP1L4 | TSSC4 | ENSP00000369915 | ENSP00000331087 | Nucleosome assembly protein 1-like 4; Acts as histone chaperone in nucleosome assembly; Belongs to the nucleosome assembly protein (NAP) family | Protein TSSC4; Tumor suppressing subtransferable candidate 4 | 0.765 |
PARVA | SLC22A18 | ENSP00000334008 | ENSP00000369948 | Alpha-parvin; Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development (By similarity). Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and dire [...] | Solute carrier family 22 member 18; May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney; Solute carriers | 0.751 |