C2CD2 protein (human) - STRING database

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C2CD2

C2 calcium dependent domain containing 2 (696 aa)

Predicted Functional Partners:

ARHGAP10

0.912

ARHGAP26

0.826

RBBP8NL

0.753

ADPRHL1

0.718

NOL9

0.705

ZNF805

0.702

TRAPPC1

0.679

SLC25A51

0.663

TMEM158

0.659

ANKFN1

0.643

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADPRHL1	C2CD2	ENSP00000364567	ENSP00000369853	[Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1	C2 calcium dependent domain containing 2	0.718
ADPRHL1	NOL9	ENSP00000364567	ENSP00000366934	[Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1	Polynucleotide 5’-hydroxyl-kinase NOL9; Polynucleotide 5’-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5’-kinase activities. Probably binds RNA; Belongs to the Clp1 family. NOL9/GRC3 subfamily	0.561
ADPRHL1	RBBP8NL	ENSP00000364567	ENSP00000252998	[Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1	RBBP8 N-terminal-like protein; RBBP8 N-terminal like	0.681
ANKFN1	C2CD2	ENSP00000321627	ENSP00000369853	Ankyrin repeat and fibronectin type III domain containing 1	C2 calcium dependent domain containing 2	0.643
ARHGAP10	ARHGAP26	ENSP00000336923	ENSP00000274498	Rho GTPase-activating protein 10; GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity)	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42	0.836
ARHGAP10	C2CD2	ENSP00000336923	ENSP00000369853	Rho GTPase-activating protein 10; GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity)	C2 calcium dependent domain containing 2	0.912
ARHGAP26	ARHGAP10	ENSP00000274498	ENSP00000336923	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42	Rho GTPase-activating protein 10; GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity)	0.836
ARHGAP26	C2CD2	ENSP00000274498	ENSP00000369853	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42	C2 calcium dependent domain containing 2	0.826
C2CD2	ADPRHL1	ENSP00000369853	ENSP00000364567	C2 calcium dependent domain containing 2	[Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1	0.718
C2CD2	ANKFN1	ENSP00000369853	ENSP00000321627	C2 calcium dependent domain containing 2	Ankyrin repeat and fibronectin type III domain containing 1	0.643
C2CD2	ARHGAP10	ENSP00000369853	ENSP00000336923	C2 calcium dependent domain containing 2	Rho GTPase-activating protein 10; GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity)	0.912
C2CD2	ARHGAP26	ENSP00000369853	ENSP00000274498	C2 calcium dependent domain containing 2	Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42	0.826
C2CD2	NOL9	ENSP00000369853	ENSP00000366934	C2 calcium dependent domain containing 2	Polynucleotide 5’-hydroxyl-kinase NOL9; Polynucleotide 5’-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5’-kinase activities. Probably binds RNA; Belongs to the Clp1 family. NOL9/GRC3 subfamily	0.705
C2CD2	RBBP8NL	ENSP00000369853	ENSP00000252998	C2 calcium dependent domain containing 2	RBBP8 N-terminal-like protein; RBBP8 N-terminal like	0.753
C2CD2	SLC25A51	ENSP00000369853	ENSP00000366945	C2 calcium dependent domain containing 2	Solute carrier family 25 member 51	0.663
C2CD2	TMEM158	ENSP00000369853	ENSP00000422431	C2 calcium dependent domain containing 2	Transmembrane protein 158; Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide	0.659
C2CD2	TRAPPC1	ENSP00000369853	ENSP00000302783	C2 calcium dependent domain containing 2	Trafficking protein particle complex subunit 1; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET5 subfamily	0.679
C2CD2	ZNF805	ENSP00000369853	ENSP00000412999	C2 calcium dependent domain containing 2	Zinc finger protein 805; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.702
NOL9	ADPRHL1	ENSP00000366934	ENSP00000364567	Polynucleotide 5’-hydroxyl-kinase NOL9; Polynucleotide 5’-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5’-kinase activities. Probably binds RNA; Belongs to the Clp1 family. NOL9/GRC3 subfamily	[Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1	0.561
NOL9	C2CD2	ENSP00000366934	ENSP00000369853	Polynucleotide 5’-hydroxyl-kinase NOL9; Polynucleotide 5’-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5’-kinase activities. Probably binds RNA; Belongs to the Clp1 family. NOL9/GRC3 subfamily	C2 calcium dependent domain containing 2	0.705

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