| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C1orf54 | ZNF768 | ENSP00000358098 | ENSP00000369777 | Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54 | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.533 |
| CORO2B | ZNF768 | ENSP00000454783 | ENSP00000369777 | Coronin-2B; May play a role in the reorganization of neuronal actin structure; Belongs to the WD repeat coronin family | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.453 |
| DNMBP | FANCI | ENSP00000315659 | ENSP00000310842 | Dynamin-binding protein; Scaffold protein that links dynamin with actin- regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity); Classical BAR domain containing | Fanconi anemia group I protein; Plays an essential role in the repair of DNA double- strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA- binds both single- stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage; Fanconi anemia complementation groups | 0.566 |
| DNMBP | RAPGEF1 | ENSP00000315659 | ENSP00000361263 | Dynamin-binding protein; Scaffold protein that links dynamin with actin- regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity); Classical BAR domain containing | Rap guanine nucleotide exchange factor 1; Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth | 0.667 |
| DNMBP | ZNF768 | ENSP00000315659 | ENSP00000369777 | Dynamin-binding protein; Scaffold protein that links dynamin with actin- regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity); Classical BAR domain containing | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.739 |
| EPHB2 | ZNF768 | ENSP00000363763 | ENSP00000369777 | Ephrin type-B receptor 2; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral corte [...] | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.533 |
| FANCI | DNMBP | ENSP00000310842 | ENSP00000315659 | Fanconi anemia group I protein; Plays an essential role in the repair of DNA double- strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA- binds both single- stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage; Fanconi anemia complementation groups | Dynamin-binding protein; Scaffold protein that links dynamin with actin- regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity); Classical BAR domain containing | 0.566 |
| FANCI | RAPGEF1 | ENSP00000310842 | ENSP00000361263 | Fanconi anemia group I protein; Plays an essential role in the repair of DNA double- strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA- binds both single- stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage; Fanconi anemia complementation groups | Rap guanine nucleotide exchange factor 1; Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth | 0.626 |
| FANCI | ZNF768 | ENSP00000310842 | ENSP00000369777 | Fanconi anemia group I protein; Plays an essential role in the repair of DNA double- strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA- binds both single- stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage; Fanconi anemia complementation groups | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.503 |
| GADL1 | ZNF768 | ENSP00000282538 | ENSP00000369777 | Acidic amino acid decarboxylase GADL1; May catalyze the decarboxylation of aspartate, cysteine sulfinic acid, and cysteic acid to beta-alanine, hypotaurine and taurine, respectively. Does not exhibit any decarboxylation activity toward glutamate; Belongs to the group II decarboxylase family | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.416 |
| MROH6 | ZNF768 | ENSP00000381857 | ENSP00000369777 | Maestro heat like repeat family member 6 | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.460 |
| RAPGEF1 | DNMBP | ENSP00000361263 | ENSP00000315659 | Rap guanine nucleotide exchange factor 1; Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth | Dynamin-binding protein; Scaffold protein that links dynamin with actin- regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity); Classical BAR domain containing | 0.667 |
| RAPGEF1 | FANCI | ENSP00000361263 | ENSP00000310842 | Rap guanine nucleotide exchange factor 1; Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth | Fanconi anemia group I protein; Plays an essential role in the repair of DNA double- strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA- binds both single- stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage; Fanconi anemia complementation groups | 0.626 |
| RAPGEF1 | ZNF768 | ENSP00000361263 | ENSP00000369777 | Rap guanine nucleotide exchange factor 1; Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.596 |
| RPL14 | ZNF768 | ENSP00000379506 | ENSP00000369777 | 60S ribosomal protein L14; Component of the large ribosomal subunit; Belongs to the eukaryotic ribosomal protein eL14 family | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.477 |
| WHAMM | ZNF768 | ENSP00000286760 | ENSP00000369777 | WASP homolog-associated protein with actin, membranes and microtubules; Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes. Its activity in membrane tubulation requires F-actin and interaction with microtubules. Proposed to use coordinated actin-nucleating and microtubule- binding activities of distinct WHAMM molecules to drive membrane tubule elongation; when MT-bound can recruit and remodel membrane vesicles but is prevented to activate the Arp2/3 complex. Involved as a regulator of [...] | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.470 |
| ZNF768 | C1orf54 | ENSP00000369777 | ENSP00000358098 | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54 | 0.533 |
| ZNF768 | CORO2B | ENSP00000369777 | ENSP00000454783 | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Coronin-2B; May play a role in the reorganization of neuronal actin structure; Belongs to the WD repeat coronin family | 0.453 |
| ZNF768 | DNMBP | ENSP00000369777 | ENSP00000315659 | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Dynamin-binding protein; Scaffold protein that links dynamin with actin- regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity); Classical BAR domain containing | 0.739 |
| ZNF768 | EPHB2 | ENSP00000369777 | ENSP00000363763 | Zinc finger protein 768; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Ephrin type-B receptor 2; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral corte [...] | 0.533 |
