• Version:
  • 11.0 [archived version]
STRINGSTRING
SVOPL SVOPL WBP4 WBP4 HM13 HM13 FAM50B FAM50B NAA60 NAA60 ZDBF2 ZDBF2 NAP1L5 NAP1L5 PLAGL1 PLAGL1 ZNF597 ZNF597 GNAS GNAS DIRAS3 DIRAS3
"FAM50B" - Protein FAM50B in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
FAM50BProtein FAM50B; Family with sequence similarity 50 member B (325 aa)    
Predicted Functional Partners:
WBP4
WW domain-binding protein 4; Promotes pre-mRNA splicing. A spliceosome-associated protein; may play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex (376 aa)
     
 
  0.594
ZNF597
Zinc finger protein 597; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (424 aa)
       
 
  0.563
NAP1L5
Nucleosome assembly protein 1 like 5 (182 aa)
     
   
  0.545
ZDBF2
DBF4-type zinc finger-containing protein 2; Zinc finger DBF-type containing 2 (2354 aa)
           
  0.530
HM13
Histocompatibility minor 13 (426 aa)
     
 
  0.523
NAA60
N-alpha-acetyltransferase 60; N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol. Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences; Belongs to the acet [...] (242 aa)
     
   
  0.521
DIRAS3
GTP-binding protein Di-Ras3; RAS type GTPase family (229 aa)
       
 
  0.498
SVOPL
Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily (492 aa)
           
  0.489
PLAGL1
Zinc finger protein PLAGL1; Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide; Belongs to the krueppel C2H2-type zinc-finger protein family (463 aa)
       
 
  0.480
GNAS
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity) (1037 aa)
           
  0.472
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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