node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGFG2 | CCDC85C | ENSP00000300176 | ENSP00000369592 | Arf-GAP domain and FG repeat-containing protein 2; ArfGAP with FG repeats 2; ArfGAPs | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | 0.604 |
ARHGAP21 | CCDC85C | ENSP00000379709 | ENSP00000369592 | Rho GTPase-activating protein 21; Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions; PDZ domain containing | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | 0.836 |
ARHGAP23 | CCDC85C | ENSP00000481862 | ENSP00000369592 | Rho GTPase-activating protein 23; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state; PDZ domain containing | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | 0.856 |
ARVCF | CCDC85C | ENSP00000263207 | ENSP00000369592 | Armadillo repeat protein deleted in velo-cardio-facial syndrome; Involved in protein-protein interactions at adherens junctions; Belongs to the beta-catenin family | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | 0.738 |
C14orf180 | CCDC85C | ENSP00000333041 | ENSP00000369592 | Nutritionally-regulated adipose and cardiac enriched protein homolog; Chromosome 14 open reading frame 180 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | 0.707 |
CCDC184 | CCDC85C | ENSP00000320849 | ENSP00000369592 | Coiled-coil domain containing 184 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | 0.617 |
CCDC184 | SNX16 | ENSP00000320849 | ENSP00000379621 | Coiled-coil domain containing 184 | Sorting nexin-16; May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm; Belongs to the sorting nexin family | 0.502 |
CCDC85C | AGFG2 | ENSP00000369592 | ENSP00000300176 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | Arf-GAP domain and FG repeat-containing protein 2; ArfGAP with FG repeats 2; ArfGAPs | 0.604 |
CCDC85C | ARHGAP21 | ENSP00000369592 | ENSP00000379709 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | Rho GTPase-activating protein 21; Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions; PDZ domain containing | 0.836 |
CCDC85C | ARHGAP23 | ENSP00000369592 | ENSP00000481862 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | Rho GTPase-activating protein 23; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state; PDZ domain containing | 0.856 |
CCDC85C | ARVCF | ENSP00000369592 | ENSP00000263207 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | Armadillo repeat protein deleted in velo-cardio-facial syndrome; Involved in protein-protein interactions at adherens junctions; Belongs to the beta-catenin family | 0.738 |
CCDC85C | C14orf180 | ENSP00000369592 | ENSP00000333041 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | Nutritionally-regulated adipose and cardiac enriched protein homolog; Chromosome 14 open reading frame 180 | 0.707 |
CCDC85C | CCDC184 | ENSP00000369592 | ENSP00000320849 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | Coiled-coil domain containing 184 | 0.617 |
CCDC85C | PKP4 | ENSP00000369592 | ENSP00000374409 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | Plakophilin-4; Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques; Armadillo repeat containing | 0.548 |
CCDC85C | SEPT10 | ENSP00000369592 | ENSP00000380824 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | Septin-10; Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Septin GTPase family | 0.545 |
CCDC85C | SNX16 | ENSP00000369592 | ENSP00000379621 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | Sorting nexin-16; May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm; Belongs to the sorting nexin family | 0.582 |
CCDC85C | SOBP | ENSP00000369592 | ENSP00000318900 | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | Sine oculis-binding protein homolog; Implicated in development of the cochlea | 0.700 |
PKP4 | CCDC85C | ENSP00000374409 | ENSP00000369592 | Plakophilin-4; Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques; Armadillo repeat containing | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | 0.548 |
SEPT10 | CCDC85C | ENSP00000380824 | ENSP00000369592 | Septin-10; Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Septin GTPase family | Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia | 0.545 |
SNX16 | CCDC184 | ENSP00000379621 | ENSP00000320849 | Sorting nexin-16; May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm; Belongs to the sorting nexin family | Coiled-coil domain containing 184 | 0.502 |