| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATPAF1 | N4BP2L1 | ENSP00000460964 | ENSP00000369473 | ATP synthase mitochondrial F1 complex assembly factor 1; May play an essential role for the assembly of the mitochondrial F1-F0 complex | NEDD4 binding protein 2 like 1 | 0.428 |
| ATPAF1 | NAA50 | ENSP00000460964 | ENSP00000240922 | ATP synthase mitochondrial F1 complex assembly factor 1; May play an essential role for the assembly of the mitochondrial F1-F0 complex | N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity- able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear- able to acetylate H4 in vitro, but this result has not been confirmed in vivo. [...] | 0.469 |
| ATPAF1 | RAB30 | ENSP00000460964 | ENSP00000435189 | ATP synthase mitochondrial F1 complex assembly factor 1; May play an essential role for the assembly of the mitochondrial F1-F0 complex | Ras-related protein Rab-30; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins; RAB, member RAS oncog [...] | 0.464 |
| CDHR2 | N4BP2L1 | ENSP00000424565 | ENSP00000369473 | Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells; Cadhe [...] | NEDD4 binding protein 2 like 1 | 0.406 |
| DHRSX | N4BP2L1 | ENSP00000334113 | ENSP00000369473 | Dehydrogenase/reductase SDR family member on chromosome X; Involved in the positive regulation of starvation- induced autophagy; Belongs to the short-chain dehydrogenases/reductases (SDR) family | NEDD4 binding protein 2 like 1 | 0.523 |
| INTS4 | N4BP2L1 | ENSP00000434466 | ENSP00000369473 | Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex; Armadillo-like helical domain containing | NEDD4 binding protein 2 like 1 | 0.655 |
| MXRA7 | N4BP2L1 | ENSP00000348050 | ENSP00000369473 | Matrix-remodeling-associated protein 7; Matrix remodeling associated 7 | NEDD4 binding protein 2 like 1 | 0.420 |
| N4BP2L1 | ATPAF1 | ENSP00000369473 | ENSP00000460964 | NEDD4 binding protein 2 like 1 | ATP synthase mitochondrial F1 complex assembly factor 1; May play an essential role for the assembly of the mitochondrial F1-F0 complex | 0.428 |
| N4BP2L1 | CDHR2 | ENSP00000369473 | ENSP00000424565 | NEDD4 binding protein 2 like 1 | Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells; Cadhe [...] | 0.406 |
| N4BP2L1 | DHRSX | ENSP00000369473 | ENSP00000334113 | NEDD4 binding protein 2 like 1 | Dehydrogenase/reductase SDR family member on chromosome X; Involved in the positive regulation of starvation- induced autophagy; Belongs to the short-chain dehydrogenases/reductases (SDR) family | 0.523 |
| N4BP2L1 | INTS4 | ENSP00000369473 | ENSP00000434466 | NEDD4 binding protein 2 like 1 | Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex; Armadillo-like helical domain containing | 0.655 |
| N4BP2L1 | MXRA7 | ENSP00000369473 | ENSP00000348050 | NEDD4 binding protein 2 like 1 | Matrix-remodeling-associated protein 7; Matrix remodeling associated 7 | 0.420 |
| N4BP2L1 | NAA50 | ENSP00000369473 | ENSP00000240922 | NEDD4 binding protein 2 like 1 | N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity- able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear- able to acetylate H4 in vitro, but this result has not been confirmed in vivo. [...] | 0.408 |
| N4BP2L1 | RAB30 | ENSP00000369473 | ENSP00000435189 | NEDD4 binding protein 2 like 1 | Ras-related protein Rab-30; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins; RAB, member RAS oncog [...] | 0.443 |
| N4BP2L1 | ZNF114 | ENSP00000369473 | ENSP00000469998 | NEDD4 binding protein 2 like 1 | Zinc finger protein 114; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.476 |
| N4BP2L1 | ZNF483 | ENSP00000369473 | ENSP00000311679 | NEDD4 binding protein 2 like 1 | Zinc finger protein 483; May be involved in transcriptional regulation; SCAN domain containing | 0.442 |
| N4BP2L1 | ZNF589 | ENSP00000369473 | ENSP00000346729 | NEDD4 binding protein 2 like 1 | Zinc finger protein 589; May play a role in hematopoietic stem/progenitor cell differentiation. May play a role as a DNA binding-dependent transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.416 |
| NAA50 | ATPAF1 | ENSP00000240922 | ENSP00000460964 | N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity- able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear- able to acetylate H4 in vitro, but this result has not been confirmed in vivo. [...] | ATP synthase mitochondrial F1 complex assembly factor 1; May play an essential role for the assembly of the mitochondrial F1-F0 complex | 0.469 |
| NAA50 | N4BP2L1 | ENSP00000240922 | ENSP00000369473 | N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity- able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear- able to acetylate H4 in vitro, but this result has not been confirmed in vivo. [...] | NEDD4 binding protein 2 like 1 | 0.408 |
| NAA50 | RAB30 | ENSP00000240922 | ENSP00000435189 | N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity- able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear- able to acetylate H4 in vitro, but this result has not been confirmed in vivo. [...] | Ras-related protein Rab-30; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins; RAB, member RAS oncog [...] | 0.491 |
