LHFP protein (human) - STRING database

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LHFP

LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner (200 aa)

Predicted Functional Partners:

COG6

0.760

MRPS31

0.723

ASB5

0.660

HMGA2

0.640

CCNB1IP1

0.631

COX6C

0.625

CHCHD10

0.614

MS4A14

0.588

SFT2D1

0.573

ASNSD1

0.571

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB5	LHFP	ENSP00000296525	ENSP00000368908	Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity); Belongs to the ankyrin SOCS box (ASB) family	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	0.660
ASNSD1	LHFP	ENSP00000260952	ENSP00000368908	Asparagine synthetase domain containing 1	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	0.571
ASNSD1	MS4A14	ENSP00000260952	ENSP00000433761	Asparagine synthetase domain containing 1	Membrane-spanning 4-domains subfamily A member 14; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains	0.634
CCNB1IP1	COX6C	ENSP00000409896	ENSP00000428895	E3 ubiquitin-protein ligase CCNB1IP1; Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis- required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL- gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates [...]	Cytochrome c oxidase subunit 6C; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport	0.754
CCNB1IP1	HMGA2	ENSP00000409896	ENSP00000437621	E3 ubiquitin-protein ligase CCNB1IP1; Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis- required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL- gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates [...]	High mobility group protein HMGI-C; Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity); Belongs to the HMGA family	0.714
CCNB1IP1	LHFP	ENSP00000409896	ENSP00000368908	E3 ubiquitin-protein ligase CCNB1IP1; Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis- required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL- gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates [...]	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	0.631
CHCHD10	LHFP	ENSP00000418428	ENSP00000368908	Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial; May be involved in the maintenance of mitochondrial organization and mitochondrial cristae structure; Mitochondrial coiled-coil-helix-coiled-coil-helix domain containing proteins	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	0.614
COG6	LHFP	ENSP00000397441	ENSP00000368908	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Components of oligomeric golgi complex	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	0.760
COG6	MRPS31	ENSP00000397441	ENSP00000315397	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Components of oligomeric golgi complex	Mitochondrial ribosomal protein S31	0.686
COX6C	CCNB1IP1	ENSP00000428895	ENSP00000409896	Cytochrome c oxidase subunit 6C; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport	E3 ubiquitin-protein ligase CCNB1IP1; Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis- required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL- gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates [...]	0.754
COX6C	HMGA2	ENSP00000428895	ENSP00000437621	Cytochrome c oxidase subunit 6C; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport	High mobility group protein HMGI-C; Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity); Belongs to the HMGA family	0.718
COX6C	LHFP	ENSP00000428895	ENSP00000368908	Cytochrome c oxidase subunit 6C; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	0.625
HMGA2	CCNB1IP1	ENSP00000437621	ENSP00000409896	High mobility group protein HMGI-C; Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity); Belongs to the HMGA family	E3 ubiquitin-protein ligase CCNB1IP1; Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis- required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL- gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates [...]	0.714
HMGA2	COX6C	ENSP00000437621	ENSP00000428895	High mobility group protein HMGI-C; Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity); Belongs to the HMGA family	Cytochrome c oxidase subunit 6C; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport	0.718
HMGA2	LHFP	ENSP00000437621	ENSP00000368908	High mobility group protein HMGI-C; Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity); Belongs to the HMGA family	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	0.640
LHFP	ASB5	ENSP00000368908	ENSP00000296525	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity); Belongs to the ankyrin SOCS box (ASB) family	0.660
LHFP	ASNSD1	ENSP00000368908	ENSP00000260952	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	Asparagine synthetase domain containing 1	0.571
LHFP	CCNB1IP1	ENSP00000368908	ENSP00000409896	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	E3 ubiquitin-protein ligase CCNB1IP1; Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis- required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL- gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates [...]	0.631
LHFP	CHCHD10	ENSP00000368908	ENSP00000418428	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial; May be involved in the maintenance of mitochondrial organization and mitochondrial cristae structure; Mitochondrial coiled-coil-helix-coiled-coil-helix domain containing proteins	0.614
LHFP	COG6	ENSP00000368908	ENSP00000397441	LHFPL tetraspan subfamily member 6 protein; Lipoma HMGIC fusion partner	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Components of oligomeric golgi complex	0.760

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