UBAP2 protein (human) - STRING database

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UBAP2

Ubiquitin associated protein 2 (1119 aa)

Predicted Functional Partners:

ZFR

0.864

TEP1

0.742

LARP1B

0.733

MAN1A2

0.720

CDKL5

0.680

MRPS36

0.675

TBL1X

0.672

PDE4DIP

0.665

PHC3

0.651

URI1

0.641

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDKL5	UBAP2	ENSP00000369325	ENSP00000368540	Cyclin-dependent kinase-like 5; Mediates phosphorylation of MECP2; Cilia and flagella associated	Ubiquitin associated protein 2	0.680
LARP1B	MAN1A2	ENSP00000321997	ENSP00000348959	La-related protein 1B; La ribonucleoprotein domain family member 1B; Belongs to the LARP family	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)	0.728
LARP1B	PDE4DIP	ENSP00000321997	ENSP00000358363	La-related protein 1B; La ribonucleoprotein domain family member 1B; Belongs to the LARP family	Myomegalin; Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). Forms a complex with AKAP9- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement	0.631
LARP1B	PHC3	ENSP00000321997	ENSP00000420294	La-related protein 1B; La ribonucleoprotein domain family member 1B; Belongs to the LARP family	Polyhomeotic-like protein 3; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’, rendering chromatin heritably changed in its expressibility; Sterile alpha motif domain containing	0.654
LARP1B	UBAP2	ENSP00000321997	ENSP00000368540	La-related protein 1B; La ribonucleoprotein domain family member 1B; Belongs to the LARP family	Ubiquitin associated protein 2	0.733
LARP1B	URI1	ENSP00000321997	ENSP00000376097	La-related protein 1B; La ribonucleoprotein domain family member 1B; Belongs to the LARP family	Unconventional prefoldin RPB5 interactor 1; Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein; Belongs to the RNA polymerase II subunit [...]	0.656
MAN1A2	LARP1B	ENSP00000348959	ENSP00000321997	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)	La-related protein 1B; La ribonucleoprotein domain family member 1B; Belongs to the LARP family	0.728
MAN1A2	PDE4DIP	ENSP00000348959	ENSP00000358363	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)	Myomegalin; Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). Forms a complex with AKAP9- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement	0.664
MAN1A2	PHC3	ENSP00000348959	ENSP00000420294	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)	Polyhomeotic-like protein 3; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’, rendering chromatin heritably changed in its expressibility; Sterile alpha motif domain containing	0.683
MAN1A2	UBAP2	ENSP00000348959	ENSP00000368540	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)	Ubiquitin associated protein 2	0.720
MAN1A2	URI1	ENSP00000348959	ENSP00000376097	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)	Unconventional prefoldin RPB5 interactor 1; Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein; Belongs to the RNA polymerase II subunit [...]	0.641
MRPS36	UBAP2	ENSP00000256441	ENSP00000368540	Mitochondrial ribosomal protein S36	Ubiquitin associated protein 2	0.675
PDE4DIP	LARP1B	ENSP00000358363	ENSP00000321997	Myomegalin; Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). Forms a complex with AKAP9- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement	La-related protein 1B; La ribonucleoprotein domain family member 1B; Belongs to the LARP family	0.631
PDE4DIP	MAN1A2	ENSP00000358363	ENSP00000348959	Myomegalin; Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). Forms a complex with AKAP9- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)	0.664
PDE4DIP	PHC3	ENSP00000358363	ENSP00000420294	Myomegalin; Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). Forms a complex with AKAP9- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement	Polyhomeotic-like protein 3; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’, rendering chromatin heritably changed in its expressibility; Sterile alpha motif domain containing	0.626
PDE4DIP	UBAP2	ENSP00000358363	ENSP00000368540	Myomegalin; Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). Forms a complex with AKAP9- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement	Ubiquitin associated protein 2	0.665
PDE4DIP	URI1	ENSP00000358363	ENSP00000376097	Myomegalin; Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). Forms a complex with AKAP9- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement	Unconventional prefoldin RPB5 interactor 1; Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein; Belongs to the RNA polymerase II subunit [...]	0.582
PHC3	LARP1B	ENSP00000420294	ENSP00000321997	Polyhomeotic-like protein 3; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’, rendering chromatin heritably changed in its expressibility; Sterile alpha motif domain containing	La-related protein 1B; La ribonucleoprotein domain family member 1B; Belongs to the LARP family	0.654
PHC3	MAN1A2	ENSP00000420294	ENSP00000348959	Polyhomeotic-like protein 3; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’, rendering chromatin heritably changed in its expressibility; Sterile alpha motif domain containing	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)	0.683
PHC3	PDE4DIP	ENSP00000420294	ENSP00000358363	Polyhomeotic-like protein 3; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’, rendering chromatin heritably changed in its expressibility; Sterile alpha motif domain containing	Myomegalin; Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). Forms a complex with AKAP9- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement	0.626

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