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STRINGSTRING
NR0B1 NR0B1 MAGEB1 MAGEB1 MAGEB3 MAGEB3 TAB3 TAB3 SHISA2 SHISA2 CXorf21 CXorf21 MAGEB4 MAGEB4 TAF9B TAF9B GTPBP6 GTPBP6 GPR174 GPR174 SLC15A4 SLC15A4
"CXorf21" - Uncharacterized protein CXorf21 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CXorf21Uncharacterized protein CXorf21; Chromosome X open reading frame 21 (301 aa)    
Predicted Functional Partners:
SLC15A4
Solute carrier family 15 member 4; Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides; Solute carriers (577 aa)
      
 
  0.661
GTPBP6
Putative GTP-binding protein 6; Pseudoautosomal region 1 (516 aa)
            
  0.630
MAGEB3
Melanoma-associated antigen B3; MAGE family member B3 (346 aa)
            
  0.569
TAF9B
Transcription initiation factor TFIID subunit 9B; Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription (251 aa)
            
  0.529
MAGEB4
Melanoma-associated antigen B4; MAGE family member B4 (346 aa)
            
  0.515
MAGEB1
Melanoma-associated antigen B1; MAGE family member B1 (347 aa)
      
   
  0.479
GPR174
Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins; G protein-coupled receptors, Class A orphans (333 aa)
      
   
  0.467
TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3; Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor; Zinc fingers RANBP2-type (712 aa)
      
   
  0.466
SHISA2
Protein shisa-2 homolog; Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling; Shisa family members (295 aa)
            
  0.447
NR0B1
Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity); Belongs to the nuclear hormone receptor family. NR0 subfamily (470 aa)
            
  0.446
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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