| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARID3A | ARID3C | ENSP00000263620 | ENSP00000368189 | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation; AT-rich interaction domain containing | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | 0.710 |
| ARID3A | SMARCA2 | ENSP00000263620 | ENSP00000265773 | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation; AT-rich interaction domain containing | Probable global transcription activator SNF2L2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural develop [...] | 0.549 |
| ARID3A | SMARCA4 | ENSP00000263620 | ENSP00000395654 | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation; AT-rich interaction domain containing | Transcription activator BRG1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons [...] | 0.523 |
| ARID3A | SMARCB1 | ENSP00000263620 | ENSP00000263121 | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation; AT-rich interaction domain containing | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Core component of the BAF (hSWI/SNF) complex. This ATP- dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric struct [...] | 0.556 |
| ARID3C | ARID3A | ENSP00000368189 | ENSP00000263620 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | AT-rich interactive domain-containing protein 3A; Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation; AT-rich interaction domain containing | 0.710 |
| ARID3C | CBX4 | ENSP00000368189 | ENSP00000269397 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | E3 SUMO-protein ligase CBX4; E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131; Chromobox family | 0.659 |
| ARID3C | DCTN3 | ENSP00000368189 | ENSP00000259632 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | Dynactin subunit 3; Together with dynein may be involved in spindle assembly and cytokinesis; Dynactin | 0.570 |
| ARID3C | FAM205A | ENSP00000368189 | ENSP00000417711 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | Protein FAM205A; Family with sequence similarity 205 member A | 0.585 |
| ARID3C | FAM219A | ENSP00000368189 | ENSP00000392452 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | Protein FAM219A; Family with sequence similarity 219 member A | 0.641 |
| ARID3C | KIAA1161 | ENSP00000368189 | ENSP00000297625 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | Myogenesis-regulating glycosidase; Putative glycosidase. Promotes myogenesis by activating AKT signaling through the maturation and secretion of IGF2; Belongs to the glycosyl hydrolase 31 family | 0.543 |
| ARID3C | RPP25L | ENSP00000368189 | ENSP00000297613 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | Ribonuclease P protein subunit p25-like protein; May be a component of ribonuclease P or MRP | 0.633 |
| ARID3C | SMARCA2 | ENSP00000368189 | ENSP00000265773 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | Probable global transcription activator SNF2L2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural develop [...] | 0.554 |
| ARID3C | SMARCA4 | ENSP00000368189 | ENSP00000395654 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | Transcription activator BRG1; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons [...] | 0.527 |
| ARID3C | SMARCB1 | ENSP00000368189 | ENSP00000263121 | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Core component of the BAF (hSWI/SNF) complex. This ATP- dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric struct [...] | 0.574 |
| CBX4 | ARID3C | ENSP00000269397 | ENSP00000368189 | E3 SUMO-protein ligase CBX4; E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131; Chromobox family | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | 0.659 |
| DCTN3 | ARID3C | ENSP00000259632 | ENSP00000368189 | Dynactin subunit 3; Together with dynein may be involved in spindle assembly and cytokinesis; Dynactin | AT-rich interactive domain-containing protein 3C; AT-rich interaction domain containing | 0.570 |
| DCTN3 | FAM205A | ENSP00000259632 | ENSP00000417711 | Dynactin subunit 3; Together with dynein may be involved in spindle assembly and cytokinesis; Dynactin | Protein FAM205A; Family with sequence similarity 205 member A | 0.470 |
| DCTN3 | FAM219A | ENSP00000259632 | ENSP00000392452 | Dynactin subunit 3; Together with dynein may be involved in spindle assembly and cytokinesis; Dynactin | Protein FAM219A; Family with sequence similarity 219 member A | 0.495 |
| DCTN3 | KIAA1161 | ENSP00000259632 | ENSP00000297625 | Dynactin subunit 3; Together with dynein may be involved in spindle assembly and cytokinesis; Dynactin | Myogenesis-regulating glycosidase; Putative glycosidase. Promotes myogenesis by activating AKT signaling through the maturation and secretion of IGF2; Belongs to the glycosyl hydrolase 31 family | 0.414 |
| DCTN3 | RPP25L | ENSP00000259632 | ENSP00000297613 | Dynactin subunit 3; Together with dynein may be involved in spindle assembly and cytokinesis; Dynactin | Ribonuclease P protein subunit p25-like protein; May be a component of ribonuclease P or MRP | 0.524 |
