• Version:
  • 11.0 [archived version]
STRINGSTRING
C12orf73 C12orf73 PATL2 PATL2 RAI14 RAI14 CLDND2 CLDND2 PPP1R32 PPP1R32 RPS25 RPS25 DHRS13 DHRS13 ITPRIPL2 ITPRIPL2 FLOT2 FLOT2 VSIG10 VSIG10 KIAA1279 KIAA1279
"DHRS13" - Dehydrogenase/reductase SDR family member 13 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHRS13Dehydrogenase/reductase SDR family member 13; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily (377 aa)    
Predicted Functional Partners:
PATL2
Protein PAT1 homolog 2; RNA-binding protein that acts as a translational repressor; Armadillo-like helical domain containing (543 aa)
           
  0.781
RAI14
Ankycorbin; Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier; Ankyrin repeat domain containing (983 aa)
           
  0.742
KIAA1279
KIF1-binding protein; Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development; Belongs to the KIF1-binding protein family (621 aa)
     
 
  0.551
C12orf73
Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 (71 aa)
           
  0.550
CLDND2
Claudin domain containing 2 (167 aa)
           
  0.538
FLOT2
Flotillin-2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function; Belongs to the band 7/mec-2 family. Flotillin subfamily (428 aa)
 
 
   
  0.526
VSIG10
V-set and immunoglobulin domain containing 10 (540 aa)
           
  0.526
RPS25
Ribosomal protein S25 (125 aa)
           
  0.517
ITPRIPL2
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2; ITPRIP like 2 (535 aa)
           
  0.511
PPP1R32
Protein phosphatase 1 regulatory subunit 32 (425 aa)
           
  0.510
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]