| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACCSL | ASB9 | ENSP00000368109 | ENSP00000369855 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Ankyrin repeat domain containing | 0.518 |
| ACCSL | BTG4 | ENSP00000368109 | ENSP00000348300 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Protein BTG4; Shows marked antiproliferative activity, being able to induce G(1) arrest; BTG/Tob family | 0.484 |
| ACCSL | DEFB112 | ENSP00000368109 | ENSP00000319126 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Beta-defensin 112; Has antibacterial activity; Defensins, beta | 0.590 |
| ACCSL | DMRTC2 | ENSP00000368109 | ENSP00000269945 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Doublesex- and mab-3-related transcription factor C2; May be involved in sexual development; Belongs to the DMRT family | 0.529 |
| ACCSL | GOT1L1 | ENSP00000368109 | ENSP00000303077 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Putative aspartate aminotransferase, cytoplasmic 2; Glutamic-oxaloacetic transaminase 1 like 1 | 0.518 |
| ACCSL | NLRP13 | ENSP00000368109 | ENSP00000343891 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | NACHT, LRR and PYD domains-containing protein 13; Involved in inflammation; NLR family | 0.599 |
| ACCSL | PATL2 | ENSP00000368109 | ENSP00000416673 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Protein PAT1 homolog 2; RNA-binding protein that acts as a translational repressor; Armadillo-like helical domain containing | 0.558 |
| ACCSL | ST8SIA3 | ENSP00000368109 | ENSP00000320431 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R-alpha 2,8-sialyltransferase; Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for substrates with alpha-2,3-linked terminal sialic acid. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid; Belongs to the glycosyltransferase 29 family | 0.483 |
| ACCSL | TCF23 | ENSP00000368109 | ENSP00000296096 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity); Basic helix-loop-helix proteins | 0.532 |
| ACCSL | WEE2 | ENSP00000368109 | ENSP00000380675 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Wee1-like protein kinase 2; Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at ’Tyr-15’, leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at ’Tyr-15’, to ensure exit from meiosis in oocytes and promote pronuclear formation ( [...] | 0.515 |
| ASB9 | ACCSL | ENSP00000369855 | ENSP00000368109 | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Ankyrin repeat domain containing | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | 0.518 |
| ASB9 | DEFB112 | ENSP00000369855 | ENSP00000319126 | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Ankyrin repeat domain containing | Beta-defensin 112; Has antibacterial activity; Defensins, beta | 0.513 |
| ASB9 | DMRTC2 | ENSP00000369855 | ENSP00000269945 | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Ankyrin repeat domain containing | Doublesex- and mab-3-related transcription factor C2; May be involved in sexual development; Belongs to the DMRT family | 0.447 |
| ASB9 | NLRP13 | ENSP00000369855 | ENSP00000343891 | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Ankyrin repeat domain containing | NACHT, LRR and PYD domains-containing protein 13; Involved in inflammation; NLR family | 0.406 |
| ASB9 | PATL2 | ENSP00000369855 | ENSP00000416673 | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Ankyrin repeat domain containing | Protein PAT1 homolog 2; RNA-binding protein that acts as a translational repressor; Armadillo-like helical domain containing | 0.525 |
| ASB9 | ST8SIA3 | ENSP00000369855 | ENSP00000320431 | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Ankyrin repeat domain containing | Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R-alpha 2,8-sialyltransferase; Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for substrates with alpha-2,3-linked terminal sialic acid. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid; Belongs to the glycosyltransferase 29 family | 0.457 |
| ASB9 | TCF23 | ENSP00000369855 | ENSP00000296096 | Ankyrin repeat and SOCS box protein 9; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A; Ankyrin repeat domain containing | Transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity); Basic helix-loop-helix proteins | 0.423 |
| BTG4 | ACCSL | ENSP00000348300 | ENSP00000368109 | Protein BTG4; Shows marked antiproliferative activity, being able to induce G(1) arrest; BTG/Tob family | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | 0.484 |
| BTG4 | DEFB112 | ENSP00000348300 | ENSP00000319126 | Protein BTG4; Shows marked antiproliferative activity, being able to induce G(1) arrest; BTG/Tob family | Beta-defensin 112; Has antibacterial activity; Defensins, beta | 0.439 |
| BTG4 | PATL2 | ENSP00000348300 | ENSP00000416673 | Protein BTG4; Shows marked antiproliferative activity, being able to induce G(1) arrest; BTG/Tob family | Protein PAT1 homolog 2; RNA-binding protein that acts as a translational repressor; Armadillo-like helical domain containing | 0.495 |
