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STRINGSTRING
N4BP2 N4BP2 ZNF770 ZNF770 NRIP3 NRIP3 POR POR HSD17B11 HSD17B11 CYP4V2 CYP4V2 PDZD7 PDZD7 PCYT1A PCYT1A ABCB6 ABCB6 DIEXF DIEXF FAM149A FAM149A
"CYP4V2" - Cytochrome P450 4V2 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CYP4V2Cytochrome P450 4V2; Omega-hydroxylase that oxidizes medium-chain saturated fatty acids and polyunsaturated omega-3 fatty acids, and which plays a role in fatty acid and steroid metabolism in the eye. Catalyzes the omega- hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12). Acts as a polyunsaturated omega-3 fatty acids hydroxylase by mediating oxidation of docosahexaenoate (DHA) to 22-hydroxydocosahexaenoate. Also produces some 21 [...] (525 aa)    
Predicted Functional Partners:
ABCB6
ATP-binding cassette sub-family B member 6, mitochondrial; Binds heme and porphyrins and functions in their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis; Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily (842 aa)
      
   
  0.599
POR
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; Belongs to the NADPH--cytochrome P450 reductase family (680 aa)
 
 
  0.594
HSD17B11
Estradiol 17-beta-dehydrogenase 11; Can convert androstan-3-alpha,17-beta-diol (3-alpha- diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor- associated antigen in cutaneous T-cell lymphoma; Belongs to the short-chain dehydrogenases/reductases (SDR) family. [...] (300 aa)
      
 
  0.578
ZNF770
Zinc finger protein 770; May be involved in transcriptional regulation; Zinc fingers C2H2-type (691 aa)
        
 
  0.567
PDZD7
PDZ domain-containing protein 7; Deafness associated genes (1033 aa)
            
  0.562
FAM149A
Protein FAM149A; Family with sequence similarity 149 member A (482 aa)
      
   
  0.538
PCYT1A
Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family (367 aa)
      
 
  0.536
DIEXF
Digestive organ expansion factor homolog; Regulates the p53 pathway to control the expansion growth of digestive organs (756 aa)
            
  0.510
N4BP2
NEDD4-binding protein 2; Has 5’-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination (1770 aa)
            
  0.503
NRIP3
Nuclear receptor interacting protein 3 (241 aa)
            
  0.499
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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