SHROOM1 protein (human) - STRING database

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SHROOM1

Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation (852 aa)

Predicted Functional Partners:

SOWAHA

0.726

APEX1

0.629

NYX

0.540

SMIM5

0.530

PHLDB3

0.522

FANK1

0.518

PRSS48

0.515

UBXN8

0.506

GRXCR2

0.502

OR11G2

0.471

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APEX1	SHROOM1	ENSP00000216714	ENSP00000367950	DNA-(apurinic or apyrimidinic site) lyase; Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5’-deoxyribo [...]	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	0.629
FANK1	SHROOM1	ENSP00000357682	ENSP00000367950	Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	0.518
GRXCR2	SHROOM1	ENSP00000367214	ENSP00000367950	Glutaredoxin domain-containing cysteine-rich protein 2; Could play a role in maintaining cochlear stereocilia bundles that are involved in sound detection; Deafness associated genes	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	0.502
NYX	SHROOM1	ENSP00000340328	ENSP00000367950	Nyctalopin	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	0.540
OR11G2	PRSS48	ENSP00000349930	ENSP00000401328	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	Serine protease 48; Belongs to the peptidase S1 family	0.640
OR11G2	SHROOM1	ENSP00000349930	ENSP00000367950	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	0.471
PHLDB3	SHROOM1	ENSP00000292140	ENSP00000367950	Pleckstrin homology like domain family B member 3	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	0.522
PHLDB3	UBXN8	ENSP00000292140	ENSP00000479216	Pleckstrin homology like domain family B member 3	UBX domain-containing protein 8; Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction; UBX domain containing	0.525
PRSS48	OR11G2	ENSP00000401328	ENSP00000349930	Serine protease 48; Belongs to the peptidase S1 family	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	0.640
PRSS48	SHROOM1	ENSP00000401328	ENSP00000367950	Serine protease 48; Belongs to the peptidase S1 family	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	0.515
SHROOM1	APEX1	ENSP00000367950	ENSP00000216714	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	DNA-(apurinic or apyrimidinic site) lyase; Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5’-deoxyribo [...]	0.629
SHROOM1	FANK1	ENSP00000367950	ENSP00000357682	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing	0.518
SHROOM1	GRXCR2	ENSP00000367950	ENSP00000367214	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	Glutaredoxin domain-containing cysteine-rich protein 2; Could play a role in maintaining cochlear stereocilia bundles that are involved in sound detection; Deafness associated genes	0.502
SHROOM1	NYX	ENSP00000367950	ENSP00000340328	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	Nyctalopin	0.540
SHROOM1	OR11G2	ENSP00000367950	ENSP00000349930	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	0.471
SHROOM1	PHLDB3	ENSP00000367950	ENSP00000292140	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	Pleckstrin homology like domain family B member 3	0.522
SHROOM1	PRSS48	ENSP00000367950	ENSP00000401328	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	Serine protease 48; Belongs to the peptidase S1 family	0.515
SHROOM1	SMIM5	ENSP00000367950	ENSP00000477017	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	Small integral membrane protein 5	0.530
SHROOM1	SOWAHA	ENSP00000367950	ENSP00000367965	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	Ankyrin repeat domain-containing protein SOWAHA; Sosondowah ankyrin repeat domain family member A; Belongs to the SOWAH family	0.726
SHROOM1	UBXN8	ENSP00000367950	ENSP00000479216	Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation	UBX domain-containing protein 8; Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction; UBX domain containing	0.506

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