• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM47B FAM47B CHDC2 CHDC2 CXorf30 CXorf30 C12orf43 C12orf43 PRRG1 PRRG1 LANCL3 LANCL3 MAGEB16 MAGEB16 CXorf22 CXorf22 TMEM47 TMEM47 FAM47A FAM47A DYNLT3 DYNLT3
"LANCL3" - LanC-like protein 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LANCL3LanC-like protein 3; LanC like 3 (420 aa)    
Predicted Functional Partners:
PRRG1
Transmembrane gamma-carboxyglutamic acid protein 1; Proline rich and Gla domain containing (218 aa)
           
  0.767
MAGEB16
Melanoma-associated antigen B16; MAGE family member B16 (324 aa)
           
  0.745
TMEM47
Transmembrane protein 47; Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin (By similarity); Belongs to the TMEM47 family (181 aa)
           
  0.630
DYNLT3
Dynein light chain Tctex-type 3; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity); Belongs to the dynein light chain Tctex-type family (116 aa)
     
   
  0.617
C12orf43
Uncharacterized protein C12orf43; Chromosome 12 open reading frame 43 (252 aa)
           
  0.599
CHDC2
Cilia- and flagella-associated protein 47; Calponin homology domain containing 2 (502 aa)
           
  0.596
CXorf30
Cilia- and flagella-associated protein 47; Chromosome X open reading frame 30 (633 aa)
           
  0.596
CXorf22
Cilia- and flagella-associated protein 47; Chromosome X open reading frame 22 (976 aa)
           
  0.596
FAM47A
Protein FAM47A; Family with sequence similarity 47 member A (791 aa)
           
  0.586
FAM47B
Protein FAM47B; Family with sequence similarity 47 member B; Belongs to the FAM47 family (645 aa)
           
  0.561
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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