| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANKRD1 | SRPX | ENSP00000360762 | ENSP00000367794 | Ankyrin repeat domain-containing protein 1; May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells; Ankyrin repeat domain containing | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | 0.501 |
| BCL9 | PYGO1 | ENSP00000234739 | ENSP00000302327 | B-cell CLL/lymphoma 9 protein; Involved in signal transduction through the Wnt pathway. Promotes beta-catenin’s transcriptional activity (By similarity); Belongs to the BCL9 family | Pygopus homolog 1; Involved in signal transduction through the Wnt pathway; PHD finger proteins | 0.999 |
| BCL9 | SRPX | ENSP00000234739 | ENSP00000367794 | B-cell CLL/lymphoma 9 protein; Involved in signal transduction through the Wnt pathway. Promotes beta-catenin’s transcriptional activity (By similarity); Belongs to the BCL9 family | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | 0.731 |
| BRS3 | SRPX | ENSP00000359682 | ENSP00000367794 | Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | 0.800 |
| INTS8 | PAMR1 | ENSP00000430338 | ENSP00000482899 | Integrator complex subunit 8; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes | Inactive serine protease PAMR1; May play a role in regeneration of skeletal muscle; Belongs to the peptidase S1 family | 0.473 |
| INTS8 | SRPX | ENSP00000430338 | ENSP00000367794 | Integrator complex subunit 8; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | 0.557 |
| MRPL54 | POFUT2 | ENSP00000331849 | ENSP00000339613 | Mitochondrial ribosomal protein L54 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and l [...] | 0.678 |
| MRPL54 | SRPX | ENSP00000331849 | ENSP00000367794 | Mitochondrial ribosomal protein L54 | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | 0.602 |
| PAMR1 | INTS8 | ENSP00000482899 | ENSP00000430338 | Inactive serine protease PAMR1; May play a role in regeneration of skeletal muscle; Belongs to the peptidase S1 family | Integrator complex subunit 8; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes | 0.473 |
| PAMR1 | SRPX | ENSP00000482899 | ENSP00000367794 | Inactive serine protease PAMR1; May play a role in regeneration of skeletal muscle; Belongs to the peptidase S1 family | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | 0.572 |
| POFUT2 | MRPL54 | ENSP00000339613 | ENSP00000331849 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and l [...] | Mitochondrial ribosomal protein L54 | 0.678 |
| POFUT2 | SRPX | ENSP00000339613 | ENSP00000367794 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and l [...] | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | 0.544 |
| PYGO1 | BCL9 | ENSP00000302327 | ENSP00000234739 | Pygopus homolog 1; Involved in signal transduction through the Wnt pathway; PHD finger proteins | B-cell CLL/lymphoma 9 protein; Involved in signal transduction through the Wnt pathway. Promotes beta-catenin’s transcriptional activity (By similarity); Belongs to the BCL9 family | 0.999 |
| PYGO1 | SRPX | ENSP00000302327 | ENSP00000367794 | Pygopus homolog 1; Involved in signal transduction through the Wnt pathway; PHD finger proteins | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | 0.731 |
| RNF182 | SRPX | ENSP00000420465 | ENSP00000367794 | E3 ubiquitin-protein ligase RNF182; E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway; Ring finger proteins | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | 0.585 |
| SRPX | ANKRD1 | ENSP00000367794 | ENSP00000360762 | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | Ankyrin repeat domain-containing protein 1; May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells; Ankyrin repeat domain containing | 0.501 |
| SRPX | BCL9 | ENSP00000367794 | ENSP00000234739 | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | B-cell CLL/lymphoma 9 protein; Involved in signal transduction through the Wnt pathway. Promotes beta-catenin’s transcriptional activity (By similarity); Belongs to the BCL9 family | 0.731 |
| SRPX | BRS3 | ENSP00000367794 | ENSP00000359682 | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family | 0.800 |
| SRPX | INTS8 | ENSP00000367794 | ENSP00000430338 | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | Integrator complex subunit 8; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes | 0.557 |
| SRPX | MRPL54 | ENSP00000367794 | ENSP00000331849 | Sushi repeat-containing protein SRPX; May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction; Sushi domain containing | Mitochondrial ribosomal protein L54 | 0.602 |
