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  • 11.0 [archived version]
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ZBTB5 ZBTB5 SAAL1 SAAL1 MYO5A MYO5A CAPZA3 CAPZA3 ACTRT2 ACTRT2 UBQLNL UBQLNL MYO1D MYO1D CCIN CCIN FTMT FTMT CCDC27 CCDC27 C1orf174 C1orf174
"ACTRT2" - Actin related protein T2 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
ACTRT2Actin related protein T2 (377 aa)    
Predicted Functional Partners:
CAPZA3
F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) (299 aa)
     
 
  0.681
UBQLNL
Ubiquilin-like protein; Ubiquilin family (475 aa)
     
 
  0.664
CCIN
Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing (588 aa)
     
 
  0.611
SAAL1
Protein SAAL1; Plays a role in promoting the proliferation of synovial fibroblasts in response to proinflammatory stimuli; Armadillo-like helical domain containing (474 aa)
           
  0.603
ZBTB5
Zinc finger and BTB domain-containing protein 5; May be involved in transcriptional regulation; BTB domain containing (677 aa)
     
 
  0.602
CCDC27
Coiled-coil domain containing 27 (656 aa)
     
   
  0.577
MYO1D
Unconventional myosin-Id; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity); Myosins, class I (1006 aa)
     
 
  0.563
C1orf174
UPF0688 protein C1orf174; Chromosome 1 open reading frame 174; Belongs to the UPF0688 family (243 aa)
           
  0.557
MYO5A
Unconventional myosin-Va; Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation; Myosins, class V (1855 aa)
     
 
  0.553
FTMT
Ferritin, mitochondrial; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation; Ferritin subunits (242 aa)
     
   
  0.549
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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