node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKEF1 | DPEP3 | ENSP00000367631 | ENSP00000268793 | Ankyrin repeat and EF-hand domain containing 1 | Dipeptidase 3; Probable metalloprotease which hydrolyzes cystinyl-bis- glycine. May be involved in meiosis (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family | 0.536 |
ANKEF1 | ELP3 | ENSP00000367631 | ENSP00000256398 | Ankyrin repeat and EF-hand domain containing 1 | Elongator complex protein 3; Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in acetylation of alpha-tubulin. May also have a methyltransferase activity. Involved in cell migration. Involved in neurogenesis. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a proc [...] | 0.624 |
ANKEF1 | FAM96B | ENSP00000367631 | ENSP00000387471 | Ankyrin repeat and EF-hand domain containing 1 | Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family | 0.541 |
ANKEF1 | GPCPD1 | ENSP00000367631 | ENSP00000368305 | Ankyrin repeat and EF-hand domain containing 1 | Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity; Belongs to the glycerophosphoryl diester phosphodiesterase family | 0.556 |
ANKEF1 | GTPBP10 | ENSP00000367631 | ENSP00000222511 | Ankyrin repeat and EF-hand domain containing 1 | GTP-binding protein 10; May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | 0.685 |
ANKEF1 | MAGIX | ENSP00000367631 | ENSP00000471299 | Ankyrin repeat and EF-hand domain containing 1 | PDZ domain-containing protein MAGIX; MAGI family member, X-linked; PDZ domain containing | 0.664 |
ANKEF1 | SF3A3 | ENSP00000367631 | ENSP00000362110 | Ankyrin repeat and EF-hand domain containing 1 | Splicing factor 3A subunit 3; Subunit of the splicing factor SF3A required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ’E’ complex; U2 small nucleolar ribonucleoprotein | 0.550 |
ANKEF1 | STK40 | ENSP00000367631 | ENSP00000362222 | Ankyrin repeat and EF-hand domain containing 1 | Serine/threonine-protein kinase 40; May be a negative regulator of NF-kappa-B and p53- mediated gene transcription; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family | 0.618 |
ANKEF1 | ZG16B | ENSP00000367631 | ENSP00000371715 | Ankyrin repeat and EF-hand domain containing 1 | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.620 |
ANKEF1 | ZNF683 | ENSP00000367631 | ENSP00000344095 | Ankyrin repeat and EF-hand domain containing 1 | Tissue-resident T-cell transcription regulator protein ZNF683; Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T-cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid orga [...] | 0.619 |
DPEP3 | ANKEF1 | ENSP00000268793 | ENSP00000367631 | Dipeptidase 3; Probable metalloprotease which hydrolyzes cystinyl-bis- glycine. May be involved in meiosis (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family | Ankyrin repeat and EF-hand domain containing 1 | 0.536 |
ELP3 | ANKEF1 | ENSP00000256398 | ENSP00000367631 | Elongator complex protein 3; Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in acetylation of alpha-tubulin. May also have a methyltransferase activity. Involved in cell migration. Involved in neurogenesis. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a proc [...] | Ankyrin repeat and EF-hand domain containing 1 | 0.624 |
FAM96B | ANKEF1 | ENSP00000387471 | ENSP00000367631 | Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family | Ankyrin repeat and EF-hand domain containing 1 | 0.541 |
FAM96B | GTPBP10 | ENSP00000387471 | ENSP00000222511 | Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family | GTP-binding protein 10; May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | 0.562 |
FAM96B | ZG16B | ENSP00000387471 | ENSP00000371715 | Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family | Zymogen granule protein 16B; Belongs to the jacalin lectin family | 0.485 |
GPCPD1 | ANKEF1 | ENSP00000368305 | ENSP00000367631 | Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity; Belongs to the glycerophosphoryl diester phosphodiesterase family | Ankyrin repeat and EF-hand domain containing 1 | 0.556 |
GPCPD1 | MAGIX | ENSP00000368305 | ENSP00000471299 | Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity; Belongs to the glycerophosphoryl diester phosphodiesterase family | PDZ domain-containing protein MAGIX; MAGI family member, X-linked; PDZ domain containing | 0.542 |
GPCPD1 | ZNF683 | ENSP00000368305 | ENSP00000344095 | Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity; Belongs to the glycerophosphoryl diester phosphodiesterase family | Tissue-resident T-cell transcription regulator protein ZNF683; Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T-cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid orga [...] | 0.508 |
GTPBP10 | ANKEF1 | ENSP00000222511 | ENSP00000367631 | GTP-binding protein 10; May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | Ankyrin repeat and EF-hand domain containing 1 | 0.685 |
GTPBP10 | FAM96B | ENSP00000222511 | ENSP00000387471 | GTP-binding protein 10; May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | Mitotic spindle-associated MMXD complex subunit MIP18; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD; Belongs to the MIP18 family | 0.562 |