node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERICH4 | IGFALS | ENSP00000367429 | ENSP00000416683 | Glutamate-rich protein 4; Glutamate rich 4 | Insulin-like growth factor-binding protein complex acid labile subunit; Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion | 0.509 |
ERICH4 | MYO18B | ENSP00000367429 | ENSP00000334563 | Glutamate-rich protein 4; Glutamate rich 4 | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.551 |
ERICH4 | NAT8L | ENSP00000367429 | ENSP00000413064 | Glutamate-rich protein 4; Glutamate rich 4 | N-acetylaspartate synthetase; Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake; Belongs to the camello family | 0.564 |
ERICH4 | PDILT | ENSP00000367429 | ENSP00000305465 | Glutamate-rich protein 4; Glutamate rich 4 | Protein disulfide-isomerase-like protein of the testis; Probable redox-inactive chaperone involved in spermatogenesis; Belongs to the protein disulfide isomerase family | 0.497 |
ERICH4 | PGA3 | ENSP00000367429 | ENSP00000322192 | Glutamate-rich protein 4; Glutamate rich 4 | Pepsin A-3; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent | 0.475 |
ERICH4 | SHISA9 | ENSP00000367429 | ENSP00000454014 | Glutamate-rich protein 4; Glutamate rich 4 | Protein shisa-9; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity); Belongs to the shisa family. SHISA9 subfamily | 0.621 |
ERICH4 | SPINK4 | ENSP00000367429 | ENSP00000369045 | Glutamate-rich protein 4; Glutamate rich 4 | Serine peptidase inhibitor, Kazal type 4 | 0.500 |
ERICH4 | TMEM184A | ENSP00000367429 | ENSP00000297477 | Glutamate-rich protein 4; Glutamate rich 4 | Transmembrane protein 184A; Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity) | 0.552 |
ERICH4 | TRIM50 | ENSP00000367429 | ENSP00000327994 | Glutamate-rich protein 4; Glutamate rich 4 | E3 ubiquitin-protein ligase TRIM50; E3 ubiquitin-protein ligase; Ring finger proteins | 0.479 |
ERICH4 | TTC29 | ENSP00000367429 | ENSP00000423505 | Glutamate-rich protein 4; Glutamate rich 4 | Tetratricopeptide repeat domain containing | 0.680 |
IGFALS | ERICH4 | ENSP00000416683 | ENSP00000367429 | Insulin-like growth factor-binding protein complex acid labile subunit; Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion | Glutamate-rich protein 4; Glutamate rich 4 | 0.509 |
IGFALS | NAT8L | ENSP00000416683 | ENSP00000413064 | Insulin-like growth factor-binding protein complex acid labile subunit; Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion | N-acetylaspartate synthetase; Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake; Belongs to the camello family | 0.497 |
IGFALS | SHISA9 | ENSP00000416683 | ENSP00000454014 | Insulin-like growth factor-binding protein complex acid labile subunit; Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion | Protein shisa-9; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity); Belongs to the shisa family. SHISA9 subfamily | 0.431 |
IGFALS | TTC29 | ENSP00000416683 | ENSP00000423505 | Insulin-like growth factor-binding protein complex acid labile subunit; Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion | Tetratricopeptide repeat domain containing | 0.462 |
MYO18B | ERICH4 | ENSP00000334563 | ENSP00000367429 | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Glutamate-rich protein 4; Glutamate rich 4 | 0.551 |
MYO18B | NAT8L | ENSP00000334563 | ENSP00000413064 | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | N-acetylaspartate synthetase; Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake; Belongs to the camello family | 0.426 |
MYO18B | TTC29 | ENSP00000334563 | ENSP00000423505 | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Tetratricopeptide repeat domain containing | 0.497 |
NAT8L | ERICH4 | ENSP00000413064 | ENSP00000367429 | N-acetylaspartate synthetase; Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake; Belongs to the camello family | Glutamate-rich protein 4; Glutamate rich 4 | 0.564 |
NAT8L | IGFALS | ENSP00000413064 | ENSP00000416683 | N-acetylaspartate synthetase; Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake; Belongs to the camello family | Insulin-like growth factor-binding protein complex acid labile subunit; Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion | 0.497 |
NAT8L | MYO18B | ENSP00000413064 | ENSP00000334563 | N-acetylaspartate synthetase; Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake; Belongs to the camello family | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.426 |