C12orf73 protein (human) - STRING database

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C12orf73

Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 (71 aa)

Predicted Functional Partners:

CLDND2

0.587

ANKRD39

0.559

PPP1R32

0.559

FAM65A

0.557

DHRS13

0.550

NPEPL1

0.511

GPN3

0.495

ZMAT2

0.491

R3HDM2

0.491

SCNM1

0.479

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD39	C12orf73	ENSP00000377170	ENSP00000367330	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	0.559
ANKRD39	CLDND2	ENSP00000377170	ENSP00000291715	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	Claudin domain containing 2	0.531
ANKRD39	DHRS13	ENSP00000377170	ENSP00000368173	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	Dehydrogenase/reductase SDR family member 13; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	0.473
ANKRD39	FAM65A	ENSP00000377170	ENSP00000400099	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	Rho family-interacting cell polarization regulator 1; Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation; Belongs to the RIPOR family	0.484
ANKRD39	GPN3	ENSP00000377170	ENSP00000442770	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	GPN-loop GTPase 3; Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family	0.435
ANKRD39	NPEPL1	ENSP00000377170	ENSP00000348395	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	Probable aminopeptidase NPEPL1; Probably catalyzes the removal of unsubstituted N- terminal amino acids from various peptides; Aminopeptidases	0.428
ANKRD39	PPP1R32	ENSP00000377170	ENSP00000344140	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	Protein phosphatase 1 regulatory subunit 32	0.491
ANKRD39	R3HDM2	ENSP00000377170	ENSP00000317903	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	R3H domain containing 2	0.420
ANKRD39	SCNM1	ENSP00000377170	ENSP00000357901	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	Sodium channel modifier 1; Plays a role in RNA splicing, possibly contributing to the recognition of non-consensus donor sites	0.418
ANKRD39	ZMAT2	ENSP00000377170	ENSP00000274712	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	Zinc finger matrin-type 2; Spliceosomal B complex	0.433
C12orf73	ANKRD39	ENSP00000367330	ENSP00000377170	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family	0.559
C12orf73	CLDND2	ENSP00000367330	ENSP00000291715	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	Claudin domain containing 2	0.587
C12orf73	DHRS13	ENSP00000367330	ENSP00000368173	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	Dehydrogenase/reductase SDR family member 13; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily	0.550
C12orf73	FAM65A	ENSP00000367330	ENSP00000400099	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	Rho family-interacting cell polarization regulator 1; Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation; Belongs to the RIPOR family	0.557
C12orf73	GPN3	ENSP00000367330	ENSP00000442770	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	GPN-loop GTPase 3; Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family	0.495
C12orf73	NPEPL1	ENSP00000367330	ENSP00000348395	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	Probable aminopeptidase NPEPL1; Probably catalyzes the removal of unsubstituted N- terminal amino acids from various peptides; Aminopeptidases	0.511
C12orf73	PPP1R32	ENSP00000367330	ENSP00000344140	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	Protein phosphatase 1 regulatory subunit 32	0.559
C12orf73	R3HDM2	ENSP00000367330	ENSP00000317903	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	R3H domain containing 2	0.491
C12orf73	SCNM1	ENSP00000367330	ENSP00000357901	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	Sodium channel modifier 1; Plays a role in RNA splicing, possibly contributing to the recognition of non-consensus donor sites	0.479
C12orf73	ZMAT2	ENSP00000367330	ENSP00000274712	Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73	Zinc finger matrin-type 2; Spliceosomal B complex	0.491

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