node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASPRV1 | GLIPR1 | ENSP00000315383 | ENSP00000266659 | Retroviral-like aspartic protease 1; Gag like LTR retrotransposon derived genes | Glioma pathogenesis-related protein 1; GLI pathogenesis related family 1 | 0.573 |
ASPRV1 | GLIPR2 | ENSP00000315383 | ENSP00000367196 | Retroviral-like aspartic protease 1; Gag like LTR retrotransposon derived genes | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | 0.527 |
ASPRV1 | TMEM37 | ENSP00000315383 | ENSP00000303148 | Retroviral-like aspartic protease 1; Gag like LTR retrotransposon derived genes | Voltage-dependent calcium channel gamma-like subunit; Thought to stabilize the calcium channel in an inactivated (closed) state. Modulates calcium current when coexpressed with CACNA1G (By similarity) | 0.771 |
BECN1 | GLIPR2 | ENSP00000355231 | ENSP00000367196 | Beclin-1; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways- PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Invo [...] | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | 0.634 |
CRIP2 | GLIPR2 | ENSP00000426119 | ENSP00000367196 | Cysteine rich protein 2; LIM domain containing | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | 0.672 |
FHL1 | GLIPR2 | ENSP00000377710 | ENSP00000367196 | Four and a half LIM domains protein 1; May have an involvement in muscle development or hypertrophy; LIM domain containing | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | 0.588 |
FHL1 | TPX2 | ENSP00000377710 | ENSP00000300403 | Four and a half LIM domains protein 1; May have an involvement in muscle development or hypertrophy; LIM domain containing | Targeting protein for Xklp2; Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at ’Thr-288’ and protects this residue against dephosphorylation. TPX2 is inactivated upon binding to importin- alpha. At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activate [...] | 0.550 |
GLIPR1 | ASPRV1 | ENSP00000266659 | ENSP00000315383 | Glioma pathogenesis-related protein 1; GLI pathogenesis related family 1 | Retroviral-like aspartic protease 1; Gag like LTR retrotransposon derived genes | 0.573 |
GLIPR1 | GLIPR2 | ENSP00000266659 | ENSP00000367196 | Glioma pathogenesis-related protein 1; GLI pathogenesis related family 1 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | 0.795 |
GLIPR1 | TMEM37 | ENSP00000266659 | ENSP00000303148 | Glioma pathogenesis-related protein 1; GLI pathogenesis related family 1 | Voltage-dependent calcium channel gamma-like subunit; Thought to stabilize the calcium channel in an inactivated (closed) state. Modulates calcium current when coexpressed with CACNA1G (By similarity) | 0.418 |
GLIPR1L1 | GLIPR2 | ENSP00000310770 | ENSP00000367196 | GLIPR1-like protein 1; Plays a role in the binding between sperm and oocytes. Component of epididymosomes, one type of membranous microvesicules which mediate the transfer of lipids and proteins to spermatozoa plasma membrane during epididymal maturation. Also component of the CD9-positive microvesicules found in the cauda region; GLI pathogenesis related family 1 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | 0.654 |
GLIPR2 | ASPRV1 | ENSP00000367196 | ENSP00000315383 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | Retroviral-like aspartic protease 1; Gag like LTR retrotransposon derived genes | 0.527 |
GLIPR2 | BECN1 | ENSP00000367196 | ENSP00000355231 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | Beclin-1; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways- PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Invo [...] | 0.634 |
GLIPR2 | CRIP2 | ENSP00000367196 | ENSP00000426119 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | Cysteine rich protein 2; LIM domain containing | 0.672 |
GLIPR2 | FHL1 | ENSP00000367196 | ENSP00000377710 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | Four and a half LIM domains protein 1; May have an involvement in muscle development or hypertrophy; LIM domain containing | 0.588 |
GLIPR2 | GLIPR1 | ENSP00000367196 | ENSP00000266659 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | Glioma pathogenesis-related protein 1; GLI pathogenesis related family 1 | 0.795 |
GLIPR2 | GLIPR1L1 | ENSP00000367196 | ENSP00000310770 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | GLIPR1-like protein 1; Plays a role in the binding between sperm and oocytes. Component of epididymosomes, one type of membranous microvesicules which mediate the transfer of lipids and proteins to spermatozoa plasma membrane during epididymal maturation. Also component of the CD9-positive microvesicules found in the cauda region; GLI pathogenesis related family 1 | 0.654 |
GLIPR2 | MYO15A | ENSP00000367196 | ENSP00000205890 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | Unconventional myosin-XV; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Required for the arrangement of stereocilia in mature hair bundles (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.616 |
GLIPR2 | SH3RF1 | ENSP00000367196 | ENSP00000284637 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | E3 ubiquitin-protein ligase SH3RF1; Acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9) (By similarity). May be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane; Belongs to the SH3RF family | 0.583 |
GLIPR2 | TMEM37 | ENSP00000367196 | ENSP00000303148 | Golgi-associated plant pathogenesis-related protein 1; GLI pathogenesis related 2; CAP superfamily | Voltage-dependent calcium channel gamma-like subunit; Thought to stabilize the calcium channel in an inactivated (closed) state. Modulates calcium current when coexpressed with CACNA1G (By similarity) | 0.660 |