| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMELX | GPX7 | ENSP00000370088 | ENSP00000354677 | Amelogenin, X isoform; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel; Belongs to the amelogenin family | Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks; Belongs to the glutathione peroxidase family | 0.537 |
| AMELX | ZFAT | ENSP00000370088 | ENSP00000367069 | Amelogenin, X isoform; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel; Belongs to the amelogenin family | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | 0.539 |
| FOXD3 | GPX7 | ENSP00000360157 | ENSP00000354677 | Forkhead box protein D3; Binds to the consensus sequence 5’-A[AT]T[AG]TTTGTTT-3’ and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis; Forkhead boxes | Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks; Belongs to the glutathione peroxidase family | 0.718 |
| FOXD3 | ZFAT | ENSP00000360157 | ENSP00000367069 | Forkhead box protein D3; Binds to the consensus sequence 5’-A[AT]T[AG]TTTGTTT-3’ and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis; Forkhead boxes | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | 0.534 |
| GPX7 | AMELX | ENSP00000354677 | ENSP00000370088 | Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks; Belongs to the glutathione peroxidase family | Amelogenin, X isoform; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel; Belongs to the amelogenin family | 0.537 |
| GPX7 | FOXD3 | ENSP00000354677 | ENSP00000360157 | Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks; Belongs to the glutathione peroxidase family | Forkhead box protein D3; Binds to the consensus sequence 5’-A[AT]T[AG]TTTGTTT-3’ and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis; Forkhead boxes | 0.718 |
| GPX7 | ZFAT | ENSP00000354677 | ENSP00000367069 | Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks; Belongs to the glutathione peroxidase family | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | 0.642 |
| KLHL29 | ZFAT | ENSP00000420659 | ENSP00000367069 | Kelch-like protein 29; Kelch like family member 29; BTB domain containing | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | 0.501 |
| LCORL | NCAPG | ENSP00000371661 | ENSP00000251496 | Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity) | Condensin complex subunit 3; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases; Armadillo-like helical domain containing | 0.860 |
| LCORL | ZFAT | ENSP00000371661 | ENSP00000367069 | Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity) | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | 0.564 |
| NCAPG | LCORL | ENSP00000251496 | ENSP00000371661 | Condensin complex subunit 3; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases; Armadillo-like helical domain containing | Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity) | 0.860 |
| NCAPG | ZFAT | ENSP00000251496 | ENSP00000367069 | Condensin complex subunit 3; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases; Armadillo-like helical domain containing | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | 0.772 |
| NFYC | ZFAT | ENSP00000396620 | ENSP00000367069 | Nuclear transcription factor Y subunit gamma; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5’- CCAAT-3’ box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | 0.688 |
| STARD13 | ZFAT | ENSP00000338785 | ENSP00000367069 | StAR-related lipid transfer protein 13; GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | 0.570 |
| TG | ZFAT | ENSP00000220616 | ENSP00000367069 | Thyroglobulin; Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3); Belongs to the type-B carboxylesterase/lipase family | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | 0.571 |
| TMEM247 | ZFAT | ENSP00000388684 | ENSP00000367069 | Transmembrane protein 247 | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | 0.592 |
| ZFAT | AMELX | ENSP00000367069 | ENSP00000370088 | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | Amelogenin, X isoform; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel; Belongs to the amelogenin family | 0.539 |
| ZFAT | FOXD3 | ENSP00000367069 | ENSP00000360157 | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | Forkhead box protein D3; Binds to the consensus sequence 5’-A[AT]T[AG]TTTGTTT-3’ and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis; Forkhead boxes | 0.534 |
| ZFAT | GPX7 | ENSP00000367069 | ENSP00000354677 | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks; Belongs to the glutathione peroxidase family | 0.642 |
| ZFAT | KLHL29 | ENSP00000367069 | ENSP00000420659 | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity); Zinc fingers C2H2-type | Kelch-like protein 29; Kelch like family member 29; BTB domain containing | 0.501 |
